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More about Sal's list

Posted by Elizabeth on June 14, 2001, at 15:53:17

In reply to Medications Options You May Not Know About, posted by SalArmy4me on June 14, 2001, at 12:26:46

Great list, Sal.

> Nefazodone - great for sleep; no sexual dysfunction; no anticholinergics side-effects.

Doesn't cause changes in sleep architecture that are seen with most other ADs.

> Carbamazepine - less side effects than Lithium or divalproex sodium.

Requires periodic blood counts, can cause drowsiness, dizziness, ataxia, etc. Less likely to cause weight gain than Li+ or valproate.

> Topiramate - the newest mood-stabilizer; it promotes weight loss.

...and is often used for just that purpose.

> Desipramine - the least side-effects of all the Tricyclics; one of the few NRIs except for reboxetine.

Nortriptyline is a good alternative for people who find desipramine overly activating.

> High-dose Venlafaxine - at higher doses Venlafaxine affects more chemicals than SSRIs.

I'd add sibutramine, which has similar chemical and pharmacological properties to venlafaxine, but is an order of magnitude more potent.

> Buspirone - an effective antidepressant and anxiolytic at high doses (60-90mg).

The "high doses" part can't be stressed enough.

> Dopamine Agonists - Pramipexole has two studies on it (I took it).

Pramipexole is a relatively selective D3 agonist. It seems to be more effective for our purposes than bromocriptine, amantadine, pergolide, etc.

> "Power Combinations" - Remeron+Effexor; Wellbutrin+Remeron, Remeron + Prozac.

A great one that I heard about: Remeron + Effexor + Wellbutrin + Lamictal + Provigil. (overkill??? :-) )

> Augmentation of anything you have tried before with Lithium, Pindolol, or Buspar (I took pindolol).

Or thyroid hormones, psychostimulants, low-dose atypical antipsychotics, ...

> Provigil - a stimulant that is possibly effective.

Although not for its official indication (narcolepsy)!

> Irreversable MAOIs - Phenelzine, Tranylcypromine. Extremely Effective.

And safer than their reputation would lead one to believe.

> MAOI-B - Selegiline, an antidepressant almost comparable to Phenelzine at 60 mg.

More activating than phenelzine; no propensity for weight gain, and less orthostatic hypotension; probably a less effective anxiolytic (no GABA-ergic effect), may cause anxiety or agitation. Will cause false positives on drug tests for amphetamine (metabolites include the less-desirable levo- isomors of amphetamine and methamphetamine).

-elizabeth


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Psycho-Babble Medication | Framed

poster:Elizabeth thread:66464
URL: http://www.dr-bob.org/babble/20010612/msgs/66497.html