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Re: Prozac--sometimes more is less

Posted by medlib on May 15, 2001, at 16:22:37

In reply to Prozac and Zyprexa combination, posted by Sergios on May 15, 2001, at 10:47:32

Sergios--

You might want to consider trying just 20mg Prozac/day with your Zyprexa before giving up on Prozac altogether.

I began taking 20mg Prozac the first week it was on the market and it was a lifesaver for years. When it finally pooped out 18 months ago, my pdoc began trying other drugs. Recently I "added back" 20mg. Prozac to my med cocktail with very good results. Then I moved up to 30mg./day at pdoc's suggestion that "maybe more is better." Within a week I felt worse; by the third week I was *much* worse and was having active suicidal thoughts for the first time in over a year. I returned to 20 mg. and, a week later, was inching back to "better." NOW I remember why I took only 20mg./day for so many years.

Prozac is a slow-motion drug; I believe that it has the longest half-life of any psychoactive med. Its full effects may not be apparent for 6-8 weeks, and may continue to build for months in some. (Obviously, I'm don't think that intolerable side effects should be endured for that long.) What I 'm suggesting is that, with Prozac, the *direction* of week-to-week changes is more significant than the nature or amount of those changes. The adage "only time will tell" was never more true than with Prozac.

Over the 18 months I've followed this board, a significant number of posters have had a "less is more" reaction to a variety of meds (hence, our motto YMMV.} Many people have found Zyprexa plus Prozac to be a powerful combination (JohnL on this board, for example). Perhaps, you just need a bit less "power."

Well wishes---medlib


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