Posted by danf on March 14, 2001, at 7:14:44
In reply to Re: restless leg syndrome/muscle twitches , posted by LMM on March 14, 2001, at 6:32:19
The twitches are different from the RLS. RLS is mediated by nerves, it is kind of like an aberrant reflex. a funny side note is that they are common in dogs on no meds.
back to people.
twitches are common with SSRIs & effexor.Twitches are from increased excitability of muscle fibrils, or from the neuromuscular junction /muscle-nerve receptor area. They are bothersome but not dangerous.
I have never seen any good explination for the myalgias ( & I have those from time to time too, mainly in quadraceps muscles when walking up stairs ). Supposedly this pain is from some minor alteration in muscle or muscle membrane metabolism. myalgias are also common with SSRIs.
serotoninergic meds increase this excitability as does epi & nor-epinephrine .... blood pH changes caused by rapid breathing also affect the muscles, along with serum dissolved Calcium levels.
poster:danf
thread:56156
URL: http://www.dr-bob.org/babble/20010310/msgs/56475.html