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Re: Smoker with Bipolar/ADD? This new drug may help » AndrewB

Posted by SLS on February 23, 2001, at 12:36:44

In reply to Re: Smoker with Bipolar/ADD? This new drug may help , posted by AndrewB on February 23, 2001, at 8:53:49

Thanks, Andrew.

I have asked everyone I could think of what is meant by a "partial agonist", but have been repeatedly disappointed. This includes psychopharmacologist and pharmacists. One doctor was even a clinical investigator studying both buspirone and gepirone! I feel pretty smart as my best guess is consistent with the definition. It is frustrating to have to guess at so many technical terms based on the context of medical literature. Guesses are just guesses, educated or not. Your URL will help me immensely.

> Scott, you make a great cautionary point about nicotine antagonists being depressives. However it is my hunch that at low doses mecamylamine is actually partial agonist and only when the dosage is increased does it become an antagonist.

> I base this on a study that showed small doses of mecamylamine to significantly improve the memory of rats and primates, both aged and healthy.

I would like to see this study. Where can I find it?


- Scott

 

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