Posted by Eric on February 9, 2001, at 14:41:47
In reply to Ziprasidone (Zeldox) Approved !, posted by SLS on February 6, 2001, at 10:03:19
The reason to get a little excited about Zeldox is not due to the fact it is another new anti-psychotic. The reason to get a little excited about this new medication is due to the fact it is the ONLY neuroleptic on the market in the USA which has automatic built in antidepressant properties.
Zeldox is reported to have built in, moderate serotonin and norephinephrine reuptake properties in addition to its anti-psychotic properties. What this means is that this drug could possibly be used all by itself to treat some cases of depression. None of the other anti-psychotics have serotonin or norephinephrine reuptake capability built into them. Thus, none of the other anti-psychotics used in the USA have any significant anti-depressant properties.
Because Zeldox has this unique, automatic built in serotonin/norephinephrine reuptake capability, it might possibly be useful used all by itself in some cases of refractory depression and psychotic depression. Usually the thing that is done is to "augment" an SSRI or Effexor with an atypical anti-psychotic, usually Zyprexa or Seroquel. With Zeldox this augmentation may not be necessary because the drug comes with both qualities...anti-psychotic and antidepressant...automatically built into it.
poster:Eric
thread:53408
URL: http://www.dr-bob.org/babble/20010131/msgs/53612.html