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NARDIL, LAMICTAL .... WHAT NEXT, WHAT ELSE? HELP!!

Posted by BK on January 28, 2001, at 19:40:31

I tried Nardil over 15 years ago after trying Imipramine and Lithium to treat my depression. Within 4 weeks I felt totally cured and I now realize, in hindsight, somewhat manic. Most amazingly, my cognitive abilities, such as writing and speaking skills and memory, increased dramatically as well. Unfortunately, the positive effects of the Nardil slowly dissipated and within 3 months I actually felt worst being on it and terminated its use. In addition to the classic symptoms, my depression manifests itself by depriving me of my sense of humor and can also make me withdrawn and uncomfortable. At other times, I can be extremely social and humorous. It seems as if my symptoms never totally leave me, but I can experience real good days (somewhat rare) and really bad, down in the dump, days as well. It’s a constant struggle that has made my life hellish at times.

In addition to the drugs I mentioned, I've also tried (in no particular order) Serzone, Parnate, Remeron, Prozac, Ritalin, Depakote, Wellbutrin, Effexor, Xanax, Zoloft, St. John’s Wort, SAM e, Cylert and most recently Lamictal. I did get some favorable cognitive benefits from the lamictal, but I was experiencing a persistent sore throat and severe dandruff with noticeable hair loss, so I stop taking it. I’ve also tried B12 injections, thyroid supplement and all sorts of vitamins and supplements and, of course, many sessions of therapy.

My questions are:

1) Has anyone experienced the same type of depressive symptoms, namely the lost of a sense of humor and the inability to connect with people (as best as I can describe it) as well as diminished cognitive skills like speaking and writing?
2) Has anyone had a similar experience of diminished effects while on Nardil? If so, does anyone know of a suitable replacement?

Based on what i've read on the boards, I'm thinking of trying Adrafinal. Any comments or suggestions would be greatly appreciated!


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poster:BK thread:52792
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