Posted by JohnL on November 10, 2000, at 4:30:21
In reply to reboxetine?, posted by Mr. Man on November 9, 2000, at 9:12:16
My symptoms are very much like yours, i.e. lack of motivation, lack of energy, no fun in normal activities, etc. At one point in my treatment Reboxetine seemed like a perfect choice, especially since serotonin meds were not doing the trick and actually making my symptom cluster a little worse instead of better.
At a mere 2mg of Reboxetine I experienced a profound intensified depression, almost suicidal-like, the very first day. I stuck with it for only a few days before throwing in the towel. It was just downright scary and dangerous for me to stay in that state of mind any longer. After stopping Reboxetine, I promptly returned to my normal depressed, yet unsuicidal, self.
In my case increasing the amounts of norepinephrine was definitely the wrong thing to do. In addition to a rapid onset of severe depression, it also caused very loud tinnitus for me, in addition to the shrivelled penis condition common to elevated norepinephrine. Sex was not possible.
Many drug trials later I discovered the best cure for my anergic melancholic depressive symptoms was either Amisulpride or Adrafinil, with both together being by far the best. Unfortunately, I'm back into the sexual dysfunction thing and having to struggle to figure out what to do about that.
Anyway, some people respond very well to Reboxetine. I think it might be wise to start very low at first. Some people on the other hand to very poorly with it. I think it must have something to do with person's adrenergic pathways. Increasing norepinephrine when it isn't low to begin with is begging for trouble. But if a deficient norepinephrine ciruitry is involved, Reboxetine will likely do some good. From what I've seen at this board, people's bodies usually either dramactically embrace or dramatically reject the Reboxetine molecule.
John
poster:JohnL
thread:48528
URL: http://www.dr-bob.org/babble/20001102/msgs/48601.html