Posted by JohnL on August 10, 2000, at 3:49:26
In reply to Possible insight into afinil dosing?, posted by Rick on August 9, 2000, at 17:22:32
I noticed the same kind of phenomenon when I used to take Zoloft. When I was increasing dosage, I would do it in an alternating step patterm like 25mg one day, 50mg the next, 25mg, 50mg and so on. Then 50mg for a while. Then 50mg a day, 75mg the next, 50mg the next, 75, and so on.
None of the SSRIs ended up being right for me, but I do recall that this fluctuating dose pattern with Zoloft worked much better than a steady dose pattern.
I wonder how you would respond at say 100mg one day, 200 the next, then 100 the next, 200, 100, etc?
Cutting pills into custom size pieces isn't easy sometimes, but as you mentioned perhaps 150mg might be the way to go. The natural variation of dosage size due to the slight inaccuracies of handcutting the pills might work to your benefit. I take 7.5mg Remeron each night as part of my cocktail. I have to divide a 30mg pill into four pieces with a large sharp knife. But the pieces hardly ever come exactly the size I want. I might actually get 5mg one day, 7.5mg the next, 6mg the next, and such. There is always just a little bit of fluctuation. I've always felt that a little daily fluctuation in dosage works better than a steady state dose. I don't know why. It's just one of those weird subtle phenomenons I've noticed by accident over the years.
John
poster:JohnL
thread:42223
URL: http://www.dr-bob.org/babble/20000729/msgs/42487.html