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--Another variable in the mix: trazodone » erik.mx

Posted by erik.mx on July 2, 2000, at 16:11:21

In reply to Switching from Wellbutrin SR to Reboxetine, posted by erik.mx on June 30, 2000, at 13:04:05

I too am interested in Robert's question. At the site KarenB directed me to, I read that impotence generally occurs at higher frequency with doses exceeding 8 mg/day (4 mg b.i.d). At this time, I don't expect to exceed that level.

My new question, however, is in regards to a second AD that I take, trazodone (Desyrel), to help me sleep. This is in addition to Klonopin, 1 mg h.s., for the same purpose. BTW, *all* these meds are prescribed to help with CFIDS/FM symptoms along with secondary depression. The dosage for the trazodone is low, i.e. 50 mg h.s., vs. the usual 150 to 400 mg/day. (A side note: trazodone is known to cause priapism at higher doses. I was previously taking trazodone at a level of 100 to 150 mg/day and while I did not experience priapism, my libido was signficantly increased, which was fine with me.) If reboxetine has a tendency to cause impotence, is it possible or likely that the trazodone will counteract that?

Is there any other concern I should have about taking reboxetine and trazodone concurrently? At the site KarenB indicated (http://www.mentalhealth.com/drug/p30-r06.html), the following is noted: "Use of reboxetine concomitantly with other antidepressants (tricyclics, MAO inhibitors, SSRIs and lithium) has not been evaluated during clinical studies." Can anybody provide further feedback on the concurrent use of reboxetine and trazodone?

Once again, your input is very much appreciated and useful!


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