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Re: newbie to this board-would love info on norpramin

Posted by University on May 4, 2000, at 1:42:20

In reply to newbie to this board-would love info on norpramin, posted by angela on May 2, 2000, at 22:27:49

> i was referred to this board today & i'm hoping to get some info on norpramin. i'm taking luvox currently for OCD and my pdoc has decided to add norpramin to the mix. i started out 2 years ago on zoloft and had bothersome side effects and begged him to switch me to celexa. i loved the celexa!! very few side effects and really no OCD or depression problems. unfortunately, i had a major OCD attack coupled with depression about a month ago and he took me off the celexa and started me on the luvox. i've never heard of norpramin, so any info would be greatly appreciated. how does it interact with luvox? can i take them at the same time? what kinds of side effects can i expect (he mentioned dry mouth, but i read about weight gain, increased appetite for sweets, excessive sweating...). thanks a bunch!

Norpramin is a brand of desipramine, which is a tricyclic antidepressant.

Desipramine affects mainly norepinephrine (as opposed to serotonin).

I can't remember what neuro Luvox works on primarily, or if it affects more than one.

You really must be careful when adding a TCA to another AD, as they often potentiate each other. There have been deaths reported (very few) in those who took an SSRI with a TCA because the latter drug potentiated the former--or vice versa, not sure.

Anyway, when I took a very modest dose of desipramine for a couple months the main side effect was PROFUSE sweating--when I was at the gym it was really awful, but even in normal situations it was bad.

I also experienced dry mouth, urinary retention, and... well that's about it I suppose. In any case, it didnt' seem to help me.

Good luck,
JM


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