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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 7 to 31 of 31. Go back in thread:
Posted by ed_uk on December 6, 2004, at 5:55:41
In reply to Re: drug of choice, posted by verne on December 6, 2004, at 2:05:06
People who have used a variety of sedatives seem to prefer methaqualone (Quaalude). What is it that makes methaqualone so 'euphoric'?
Ed.
Posted by thinkfast on December 7, 2004, at 19:52:33
In reply to Re: drug of choice, posted by alexandra_k on December 5, 2004, at 2:30:16
OK...hallucinogens effect serotonin
speed efx dopamine
pot efx serotonin & ?
nicotine efx dopamine
They should go on this crap when they try and pick out ur meds! Do the pdocs use any of your drug abuse past factor into what drugs they try on u? It kinda sux that if you have an amphetamine abuse past that they don't give you any of that, but in most cases I would say this is a good idea. But, what if it were something you 'needed'? Although, this all seems like just a replacement for the prior chemical. That in itself makes me feel weak or something. Seems the only way to get away completely is to quit it all and go through hell for a while to get over it.
Posted by leendee on December 8, 2004, at 17:35:58
In reply to Re: To those who have taken Quaalude, posted by ed_uk on December 6, 2004, at 5:55:41
I took quaaludes 25 years ago when you could get them. They are much more intense than benzos or barbiturates... They make you VERY horny, and your whole body feels wonderful, euphoric, like ecstacy but instead of a speedy feeling, a relaxed, eventually sleepy feeling. If I could find them I'd take them again!
Posted by ed_uk on December 9, 2004, at 5:58:18
In reply to Re: To those who have taken Quaalude, posted by leendee on December 8, 2004, at 17:35:58
Thanks Leendee,
No wonder they were so addictive!
Regards,
Ed.
Posted by ed_uk on December 12, 2004, at 7:13:58
In reply to Re: To those who have taken Quaalude » leendee, posted by ed_uk on December 9, 2004, at 5:58:18
In fact, the subjective effects of Quaalude which you report make it sound more like alcohol than other sedatives.
Ed.
Posted by thinkfast on December 14, 2004, at 7:14:06
In reply to drug of choice, posted by thinkfast on December 5, 2004, at 1:28:48
anyone have any other thoughts besides quaaludes?
Posted by mattw84 on December 14, 2004, at 21:39:23
In reply to Re: drug of choice, posted by thinkfast on December 14, 2004, at 7:14:06
The H is by far my favorite -- or at least was 2 years ago. If I ever do it again it will be the last time... and so the story goes for most who ever get 'clean.'
Don't touch the tar, it'll consume you.
Posted by simcha on December 16, 2004, at 2:38:55
In reply to drug of choice, posted by thinkfast on December 5, 2004, at 1:28:48
Codeine is just yummy. So is dihydrocodeine. Vicodin is lovely.
I would love to try just pure opium. I would grow the poppies if I didn't think that I wouldn't fall down into a coma eventually.
That plant's effects are just too lovely for words.
A warm sense of peace. All is right with the world. I actually pray to the Gods and Goddesses when I've been high on opiates (they were left over scripts) that they have put me on this Earth and that it is so lovely.
The sad thing is that you must come down and you can't live a normal life high on opiates.
Oh well... Nothing's perfect...
Current cocktail
Celexa 40mg. am
WellbutrinXL 300mg pm
Neurontin 600mg pm (or more as needed)Simcha
Posted by thinkfast on December 16, 2004, at 8:26:41
In reply to Re: drug of choice... Opiates and Opioids, posted by simcha on December 16, 2004, at 2:38:55
Opiates! :::Drools:::: I've pondered the idea of growing some poppies myself cuz I've never tried pure opium. You can order the dried pods off some places on the internet for "decorative" purposes, and they still have the opium in them. Of course it's dried out, so it just wouldn't be the same as getting out a kitchen knife and collecting a couple grams of pure black tar! ;-) But anyway, I agree with you. Nothing is quite the same as the serenity of the opiate high. So, let's break out the robes and incense and meditate a while.......peace
Posted by thinkfast on December 16, 2004, at 8:27:56
In reply to Re: drug of choice... Opiates and Opioids, posted by simcha on December 16, 2004, at 2:38:55
Posted by thinkfast on December 16, 2004, at 8:30:42
In reply to The H, posted by mattw84 on December 14, 2004, at 21:39:23
Never tried H-ron b4....how much different is it than a bunch of hydrocodone or a morphine pill?
Posted by kazoo on December 17, 2004, at 2:05:55
In reply to Re: To those who have taken Quaalude, posted by ed_uk on December 6, 2004, at 5:55:41
> What is it that makes methaqualone so 'euphoric'?
>
> Ed.You mean "soporific"? Simple. Your brain.
Happy Holidays.
(I remain, the elusive)
kazoo
Posted by alexandra_k on December 21, 2004, at 0:00:13
In reply to Re: The H » mattw84, posted by thinkfast on December 16, 2004, at 8:30:42
I found it to be good when you are sitting or lying down but:
If you drink anything you spew
If you eat anything you spew
If you stand up you spew
And if you walk around then you most definately spew.Sigh. Back to the hallucinagens for me :-)
Posted by alexandra_k on December 21, 2004, at 18:20:55
In reply to Re: The H, posted by alexandra_k on December 21, 2004, at 0:00:13
Actually peoples have told me that I must have had too much to have done all that spewing. But if that is the case then I wanted more high and less spewage. I guess opiates are just not the drug for me (though I have yet to try poppies too)...
Posted by amberlicious on December 27, 2004, at 21:14:17
In reply to drug of choice, posted by thinkfast on December 5, 2004, at 1:28:48
I recently quit speed. What a horrible drug. It has to be the dirtiest thing I've ever put in my body. I did it off and on for two years and "quit" many times. I've been trying to figure out my attraction to it since I always hated amphetamines.
When I coupled it with alcohol, my social phobia was drastically reduced. I don't know if I'd call it euphoric, but I felt hella good. It also got in me in a lot of trouble. For a while I was giving my dealer lap dances in exchange for the drug. Then I bought it with money that was intended for greater purposes, rent, my family, and getting out of debt.
Right now I'm crying and I don't know if its from guilt or from cravings. It wasn't until several weeks ago that I realized that I of all people, being bipolar, had no business doing this drug. Maybe I liked speed because it gave me more control over the lows and highs. At least I could decide when they happen and how long they would last.
Sorry I rambled on so long. This has been prevalent on my mind. As far as your question goes, I don't know a prescription substitute for speed except ADHD meds like adderal and ritalin.
These are actually stimulants unlike straterra.licious
Posted by thinkfast on December 28, 2004, at 3:12:18
In reply to Re: drug of choice » thinkfast, posted by amberlicious on December 27, 2004, at 21:14:17
I've "quit" many times as well :-) Boredom is what gets me into trouble, especially in the winter when there's nothing to do. I've stayed away for a few weeks and still have people calling me wanting to know if I want any of it. I'm done with that cr*p...I've got an appt. thurs with a new doc to talk about adderall. I still don't know if it's something I need or if it's just an addiction, but I will go ahead and try it out. That seems like the only way I will be able to tell. If I start to crave it or want to take more then I'll get away from it. If it helps, then great, but if it doesn't in the longrun...it's on to the next.
Posted by Festus on January 4, 2005, at 22:30:05
In reply to Re: drug of choice » amberlicious, posted by thinkfast on December 28, 2004, at 3:12:18
Back in the days when Lude,s could be gotten,the common factor that seemed to befall everyone that did them was loss of balance.Fall,fall,fall.People would look like they were beaten with a hose the next day.Also,getting the hiccups was common.This would usually end up as spewing.Ludes have been a C-1 drug since,well,for a while.The"Speed"that was referred to was obviously not Bi-phetamine or from a bonified source,because,if it was,there was nothing like taking a pharmacutical Black Beauty(anyone remember those?)Take one of them and get a few bottles of Ripple and some Panama Red Smoke,put on some Allman Brothers or Grateful Dead or,better yet,plug in to your Peavey amp and GOOOOO!!!
Anyone who has done this will be hard pressed to out-do it on the"drug of choice"even though this involves a bit of a mixture,but what a mixture! Festus
Posted by thinkfast on January 5, 2005, at 14:27:22
In reply to Re: drug of choice, posted by Festus on January 4, 2005, at 22:30:05
Where can I find em'???? lol...I've got a my guitar sitting next to me just waiting....I'd have to go with pink floyd though...Think I could play the comfortably numb solo on that stuff?! ;-)
Posted by Phil on January 13, 2005, at 6:50:12
In reply to Re: drug of choice, posted by thinkfast on January 5, 2005, at 14:27:22
We used to call Ludes disco bisquits long ago. My mom had some till I found them.
As was mentioned above, they really made you horny.I also used to take Mandrex which were plentiful back then. We always knew when everyone was out of Mandrex when no one had any new dents in their cars.
Ah, the follies of youth.
Posted by tenor42 on January 18, 2005, at 14:22:08
In reply to Re: The H, posted by alexandra_k on December 21, 2004, at 18:20:55
I was on buprenorphine for a little over a year. Sublingual. I lowered the dose over time with my Dr's consent. Finally I was down to 2 mg a day.....then 1/2 of that....and the last for days at 1/4 of a 2 mg subutex. I think i should have stayed on 1/4 of 2 mg for months not days. I was a freaking mess for a week. I might as well have been kicking dope...yet of course I have been living a regular life for a year,I know what is going into my body, i was under a Dr's care, he helped later with clonidine (didn't help really) and now Klonopin and Ambien to sleep. In the past when I took Ambien to sleep I needed one. This time, initially at first I needed two. I couldn't eat for a week....it was NOT EASY....but i am now an opiate free man....YAHOOOOOOO! Yeah for me...just goes to show you...IT CAN BE DONE...if I can do it anyone can.....
thought I'd share...
tenor42
Posted by Colleen D. on January 26, 2005, at 20:09:19
In reply to Re: drug of choice, posted by Festus on January 4, 2005, at 22:30:05
Posted by Phil on January 28, 2005, at 20:29:33
In reply to THREE BEERS AND A JOINT! (nm), posted by Colleen D. on January 26, 2005, at 20:09:19
Colleen D. Absolutely. That was 'my favorite cocktail.' The perfect blend.
It was self-medicating of the highest order!Phil
Posted by HoldenYosarian on February 13, 2005, at 1:08:11
In reply to drug of choice, posted by thinkfast on December 5, 2004, at 1:28:48
> Anyone have any good info or wisdom on people and their drug of choice? I've just been wondering about people knowing what chemical actually helps them out. I'm just trying to perhaps get some useful info from my drug abuse past and it's relation to the medication ordeal. Do we really know what is best for ourselves, or must we leave it up to someone else? In reality, it comes down to that anyway. Some meds work and some don't. Some meds make me crave "other" drugs less. Effexor took care of the alcohol. Seroquel gives me sleep, and I used to smoke weed everyday to get that. The last one is un-resolved. I can't decide if this is an addiction or if it is actually something that would benefit me. It's the amphetamines. I've been trying to figure this out for a year or two. I've got strattera now, but it doesn't quite hit the right spot. I can't decide if I'm being honest with myself or if I've fabricated the whole thing and now I am un-aware of my previous tracks. ::::Pulls hair out:::: I have to figure this out a.s.a.p or I "will" go insane! hehe Not quite, but any replies would be appreciated. Thanx
It really depends more on your reaction to the given drug than anything else. If you're taking something you need, you will often find that it affects you differently than others around you who are doing the same thing. For example, if the speed gives you a sense of calm, control, or KEEPS your mind from racing, then you have ADD. Of course, you can overshoot the mark, and then just speed out like the average person. But if you've ever found that you passed through a stage when you experienced the above, then you have ADD.
Posted by HoldenYosarian on February 13, 2005, at 1:14:32
In reply to Re: drug of choice... Opiates and Opioids » simcha, posted by thinkfast on December 16, 2004, at 8:26:41
> Opiates! :::Drools:::: I've pondered the idea of growing some poppies myself cuz I've never tried pure opium. You can order the dried pods off some places on the internet for "decorative" purposes, and they still have the opium in them. Of course it's dried out, so it just wouldn't be the same as getting out a kitchen knife and collecting a couple grams of pure black tar! ;-) But anyway, I agree with you. Nothing is quite the same as the serenity of the opiate high. So, let's break out the robes and incense and meditate a while.......peace
in case any of you didn't know, it's only the "Emperor" poppy that produces in any quantity
Posted by Questionmark on February 19, 2005, at 18:32:15
In reply to Re: drug of choice » alexandra_k, posted by thinkfast on December 7, 2004, at 19:52:33
> OK...hallucinogens effect serotonin
>
> speed efx dopamine
>
> pot efx serotonin & ?
>
> nicotine efx dopamine
>
> They should go on this crap when they try and pick out ur meds! Do the pdocs use any of your drug abuse past factor into what drugs they try on u? It kinda sux that if you have an amphetamine abuse past that they don't give you any of that, but in most cases I would say this is a good idea. But, what if it were something you 'needed'? Although, this all seems like just a replacement for the prior chemical. That in itself makes me feel weak or something. Seems the only way to get away completely is to quit it all and go through hell for a while to get over it.
>
Sorry, i don't mean to be too critical or anything, but what you said is really far too much of a generalization.
Some hallucinogens (e.g., mescaline-- i'm pretty sure) bind with norepinephrine (and/or other?) receptors and do not directly affect serotonin at all. And even the serotonergic psychedelics (e.g. LSD & psilocin) act much much differently than serotonergic medications like the SSRIs or what have you.
Speed & amphetamines (& cocaine) do have potent effects on dopamine, but most also generally affect norepinephrine quite strongly as well-- as well as even serotonin to some degree. i also disagree with the theory (which someone else brought up) that someone can tell if they have ADHD based on how they react to stimulants. They may be able to give you some slight idea of an indication, but i doubt anymore than that. You hear that kind of thing all the time from "lay people," but if it were that accurate it seems like professionals would have derived some kind of diagnostic method using this theory/ & these drugs.
Nicotine does have an indirect effect on dopamine release, but just about all if not all addictive drugs have a significant effect on dopamine transmission. Nicotine also only (or nearly only) binds to cholinergic nicotinic receptors, which alters the release of at least a few different neurotransmitters, not just dopamine.
So, as you can see, thinkfast's/your idea was a good one, and is a really good point in the purpose that it serves (e.g. if someone reacts very well overall to speed or cocaine then maybe s/he would do well on a pharmaceutical stimulant, or something), but is not really that practical at all on the level you were suggesting.
i hope this post was useful to at all otherwise i just typed way too much for way too long for no purpose.
This is the end of the thread.
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