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Dr. Bob is Robert Hsiung, MD,
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Posted by pontormo on June 24, 2020, at 22:37:25
Does anyone have/know of evidence about whether turmeric (or curcumin) is problematic if you've been prescribed MAOIs?
It seems that turmeric has MAOI--b inhibitory effects. I'm not sure of the strength of the effect.. But I haven't seen any evidence that it can produce any issues. I use it and was thinking of ordering a capsule form,. but I was wondering if I need to be aware of any concerns about doses, etc.
thanks, Pontormo
Posted by MightyKondrian on July 1, 2020, at 14:05:21
In reply to Tumeric and MAOIs, posted by pontormo on June 24, 2020, at 22:37:25
I wouldn't worry too much.
Many foodstuffs have MAO inhibiting compounds but far from producing a significant inhibiting effect by itself. Yes, some herbs like Rhodiola should be used with caution but their MAOI effects are just a part of there effects which are synergistic with many other compounds to produce the finale.
A few antioxidants are MAOIs, or produce that effect: Resveratrol, Quercetin & active compounds in honey, pollen and propolis (bees)and indeed Cuminoids:
https://pubmed.ncbi.nlm.nih.gov/23499958/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6385169/
https://www.tandfonline.com/doi/pdf/10.3109/14756366.2013.843171
https://www.e-sciencecentral.org/articles/SC000031864But Turmeric (curcumin) does show significant antidepressant effects. Especially in combination with other medicinal plant extracts. Here's an awesome one: https://pubmed.ncbi.nlm.nih.gov/27723543/
Babblemail me for product source.
Posted by pontormo on July 1, 2020, at 20:38:21
In reply to Re: Tumeric and MAOIs » pontormo, posted by MightyKondrian on July 1, 2020, at 14:05:21
thanks, I may have heard about tumeric as an antidepressant, but had forgotten. I'll keep that in mind.
It hadn't bothered me used with food, but I wondered if, in the doses it was found as a supplement, it might. Guess I'll give it a try.
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