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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 2 of 2. This is the beginning of the thread.
Posted by PeterMartin on March 6, 2019, at 22:17:04
This medicine works for me in a way Nardil (which I used during the year it wasn't available) couldn't.
Thank god I'm able to get it again even though it's costing me a ridiculous amount (Danish version is being imported by US company at the moment).
Random 1988 Pub Med study on Marplan. I like the Interpersonal Sensitivity mention - I definitely feel that aspect - and I think that's what gives me more focus/drive to do things.
----Arch Gen Psychiatry. 1988 Feb;45(2):120-7.
An efficacy study of isocarboxazid and placebo in depression, and its relationship to depressive nosology.
Davidson JR1, Giller EL, Zisook S, Overall JE.
Author information
Abstract
Isocarboxazid and placebo were evaluated in 130 anxious depressives. Drug was superior to placebo on depression, anxiety, interpersonal sensitivity, and global measures, and on symptoms of hostility, anxiety, obsessiveness, and psychological-cognitive components of depression. There were no significant differences between treatment effects on psychomotor and typical vegetative symptoms. Isocarboxazid was more effective than placebo in major, but not in minor, depression. It was significantly more effective in depression classified as endogenous depression or melancholia by various diagnostic criteria. Drug was more effective than placebo in atypical depression with vegetative reversal and in Brief Psychiatric Rating Scale (BPRS)-derived profiles of anxious and hostile depression; there were no drug-placebo differences in atypical depression without vegetative reversal, or in BPRS retarded and agitated/excited depression. Interpersonal sensitivity emerged as an important drug-responsive dimension.
Posted by porkpiehat on March 8, 2019, at 13:07:37
In reply to 10 days back on Marplan after yr Shortage..., posted by PeterMartin on March 6, 2019, at 22:17:04
PeterMartin I am probably six weeks off Nardil now and I want to see what life is like before getting back on that horse. I love natural sleep it feels like a luxury.
Did you do a hot switch or taper off Nardil first? What, if anything, do you take for sleep at night and daytime sedation?
of the three, Marplan was the best for sociability for me, but I found irritability spiking at higher doses, as well as racing thoughts and paranoid ideation. Nardil was best for keeping my irritability in check but with lower energy/motivation.
Is there a way for us to talk directly? My "spam" email is [xxx].
Best of luck!
This is the end of the thread.
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