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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by rjlockhart37 on February 12, 2019, at 17:15:26
i'm starting to have problems with tolerance, no it's not with meds completly, but i've noticed ... say a supplement or an antidepressant, it works for a long time then it plataues, where .. you have to take higher dose. Before i've never had tolerance problems, when i was younger or even a few years ago, then i started to notice just a blah platuea feeling after years of taking a med, and then when i took a supplement, it worked then it plataued too.....
i can't stand it, have to completly stop intake to make tolerance go away, it's very irritating and i've never had problems wiht it before, it's only been these past years
does anyone else have this same problem?
Posted by SLS on February 14, 2019, at 3:55:26
In reply to tolerance, posted by rjlockhart37 on February 12, 2019, at 17:15:26
> i'm starting to have problems with tolerance, no it's not with meds completly, but i've noticed ... say a supplement or an antidepressant, it works for a long time then it plataues, where .. you have to take higher dose. Before i've never had tolerance problems, when i was younger or even a few years ago, then i started to notice just a blah platuea feeling after years of taking a med, and then when i took a supplement, it worked then it plataued too.....
>
> i can't stand it, have to completly stop intake to make tolerance go away, it's very irritating and i've never had problems wiht it before, it's only been these past years
>
> does anyone else have this same problem?Yes.
Which drugs are you having problems with?
How far up the ladder towards remission do these drugs take you?
Your brain is no longer a virgin. It has been exposed to different chemical substances. The brain often changes in response to these exposures. The most obvious change is in the number of neurotransmitter receptors along nerve cell membranes. There are a great many other aspects of brain function that are also altered. These changes often persist long after the substance is discontinued. A drug that was used successfully once in the past often fails to work equally well upon its reintroduction.
- Scott
Posted by rjlockhart37 on February 14, 2019, at 14:03:25
In reply to Re: tolerance » rjlockhart37, posted by SLS on February 14, 2019, at 3:55:26
it's mainly my meds im taking, and other supplements, and even caffeine, drinking coffee or takin a caffeine tablet, it works then requires a higher dose, but with caffeine you there is a limit mainly of 400-600mg because anything higher than that will cause irrtibility and stressed mood. It's ... some days i can notice my meds working, and other days it's like ... blah like take them and bearly notice a difference....like only slightly. But if don't take prozac in the morning, the day ahead would be difficult. But then when take them, it's a like a plataue. It's common i think....because people have to switch antidepressants, like they've posted on this board, the wear out, where it's no longer effective. Prozac is effective but it plataued, but i'm just staying it, i'm not gonna switch. I've been on it too long, and i'm adjusted to it, familiar with it's benefits
armodafinil works ok, of course yes i've noticed a difference at higher dose, but....i guess it's just the equilibrium thing the body does to adapt
Posted by Lamdage22 on February 24, 2019, at 8:59:18
In reply to Re: tolerance, posted by rjlockhart37 on February 14, 2019, at 14:03:25
I have developed tolerance to Trazodone and to Blueberries. Both put me back in the gym for a couple of months, then I lack the motivation.
This is the end of the thread.
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