![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 2 of 2. This is the beginning of the thread.
Posted by PeterMartin on August 6, 2018, at 21:39:03
Why would adding a small dose of Marplan (10/20mg) to a normal dose of Nardil be a serious risk for Serotonin Syndrome or hypertensive crisis?
Many people combine Nardil/Marplan with Lithium which is known to increase Serotonin in the brain. I don't understand why a small dose of Marplan added to Nardil would be more risky. The hope being that it sparks Nardil to work.
I understand why Parnate + another MAOi would be extremely risky but Nardil/Marplan are both hyrdrazine based.
Posted by linkadge on August 7, 2018, at 14:43:25
In reply to Low dose Marplan + Nardil full dose - why SS?, posted by PeterMartin on August 6, 2018, at 21:39:03
Great question,
I have no idea. I have often wondered the same thing myself. Do you have any references to data suggesting you cannot combine them?
Perhaps two different MAOIs can synergistically inhibit MAO (more so than any one could).
Who knows.
Linkadge
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.