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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 11 of 11. This is the beginning of the thread.
Posted by Farshad on January 25, 2018, at 4:53:39
I have social anxiety and the only med that has ever worked is zyprexa but why ? I thought at first was becuase it blocks serotonin receptors but so does seroquel and that 1 didnt work.
Posted by Lamdage22 on January 25, 2018, at 7:20:09
In reply to why did zyprexa work but not seroquel for anxiety, posted by Farshad on January 25, 2018, at 4:53:39
I think that we cant explain everything that happens with psychiatric drugs. If you read the prescribing info you will always see it is thought that.
The mind and the brain are much more complicated that we can fathom.
Posted by Lamdage22 on January 25, 2018, at 7:22:26
In reply to Re: why did zyprexa work but not seroquel for anxiety, posted by Lamdage22 on January 25, 2018, at 7:20:09
You want a pattern drugs that do xyz help me. I dont think you will get it but good luck with that!
Posted by SLS on January 25, 2018, at 12:01:47
In reply to why did zyprexa work but not seroquel for anxiety, posted by Farshad on January 25, 2018, at 4:53:39
> I have social anxiety and the only med that has ever worked is zyprexa but why ? I thought at first was becuase it blocks serotonin receptors but so does seroquel and that 1 didnt work.
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Olanzapine (Zyprexa):
"From the thienobenzodiazepine class (TBZ), Olanzapine (2-methyl-4-(4-methyl-l-piperazinyl)-10H-thieno[2,3-b][1,5]benzodiazepine) (Zyprexa) was used as an example to demonstrate the antagonism of this class of compounds for multiples receptors including: dopamine D1-D5, α-adrenoreceptor, histamine H1, muscarinic M1-M5 and 5-HT2A, 5-HT2B, 5-HT2C, 5-HT3 and 5-HT6 receptors."
https://www.ncbi.nlm.nih.gov/pubmed/25694077
--------------------------------
Binding affinities:
- Scott
Posted by SLS on January 26, 2018, at 22:13:41
In reply to why did zyprexa work but not seroquel for anxiety, posted by Farshad on January 25, 2018, at 4:53:39
Which properties of Zyprexa do you think are responsible for the improvement in anxiety that you experience when you take it?
- Scott
Posted by farshad on January 27, 2018, at 1:40:28
In reply to Re: why did zyprexa work but not seroquel for anxiety » Farshad, posted by SLS on January 26, 2018, at 22:13:41
> Which properties of Zyprexa do you think are responsible for the improvement in anxiety that you experience when you take it?
>
>
> - Scottno idea but i think its because it does a range of things in the brain and 1 of the things happen to help me. also its an 5-HT5Aagonist I noticed.. maybe that has to do with it.
Posted by Lamdage22 on January 27, 2018, at 2:47:01
In reply to Re: why did zyprexa work but not seroquel for anxiety, posted by farshad on January 27, 2018, at 1:40:28
Social anxiety sucks man. I dont think you can predict how a drug affects you so much. Certainly being pre-psychotic doesnt help social anxiety. Or at least not in a way that you would want.
Posted by Lamdage22 on January 27, 2018, at 4:28:30
In reply to why did zyprexa work but not seroquel for anxiety, posted by Farshad on January 25, 2018, at 4:53:39
Is social anxiety your only diagnosis?
Posted by Christ_empowered on January 28, 2018, at 12:15:50
In reply to Re: why did zyprexa work but not seroquel for anxiety, posted by Lamdage22 on January 27, 2018, at 2:47:01
maybe it was a dosage issue? it take s alot of seroquel to do much of anything (except sedation). zyprexa is far more potent. it could be that your zyprexa dose was higher than the amount of seroquel you were prescribed. plus...
seroquel isn't a panacea. i hate the stuff, personally. other people respond well to it, w/o eps, td, etc., so that's a good thing.
Posted by baseball55 on January 28, 2018, at 17:00:57
In reply to Re: why did zyprexa work but not seroquel for anxiety, posted by Christ_empowered on January 28, 2018, at 12:15:50
I know we are all looking for a pill to take, but anxiety disorders - and particularly social anxiety - usually always improve with a good course of CBT therapy.
Posted by farshad on January 29, 2018, at 2:02:19
In reply to Re: why did zyprexa work but not seroquel for anxiety, posted by Christ_empowered on January 28, 2018, at 12:15:50
> maybe it was a dosage issue? it take s alot of seroquel to do much of anything (except sedation). zyprexa is far more potent. it could be that your zyprexa dose was higher than the amount of seroquel you were prescribed. plus...
>
> seroquel isn't a panacea. i hate the stuff, personally. other people respond well to it, w/o eps, td, etc., so that's a good thing.I think it was a low dosage like 2.5mg but now that I think about it I think it was the histamine antagonism that made me think it worked
This is the end of the thread.
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