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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by PeterMartin on November 8, 2016, at 18:36:22
Discounted GABA drugs show promise as antidepressants
Posted by Barbara Kennedy-Penn State November 8th, 2016http://www.futurity.org/gaba-antidepressant-drugs-1292502-2/
via:
Increasing the activity of the neurotransmitter GABA in the brains of depressed mice has antidepressant effects:
http://medicalxpress.com/news/2016-11-neurotransmitter-gaba-brains-depressed-mice.html
Posted by Hugh on November 9, 2016, at 10:43:47
In reply to Study: Increase GABA in Depressed Mice = AD effect, posted by PeterMartin on November 8, 2016, at 18:36:22
Since I've had quite a bit of experience with benzos, I found this quote from the article interesting:
"The failure of benzodiazepines to alleviate depressive symptoms is a main reason why GABA-signaling deficits have been discounted as possible causes of depressive disorders. But our research suggests that GABA is involved and that there must be other reasons for the failure of benzodiazepines."
Posted by Christ_empowered on November 9, 2016, at 13:56:30
In reply to Re: Study: Increase GABA in Depressed Mice = AD effect, posted by Hugh on November 9, 2016, at 10:43:47
back in the day, xanax was sometimes used for some forms of depression. I think the doses were higher than the 4mgs/max they recommend these days.
Posted by Jonhed on November 12, 2016, at 5:39:08
In reply to Re: Study: Increase GABA in Depressed Mice = AD effect, posted by Christ_empowered on November 9, 2016, at 13:56:30
Yes, alprazolam is used in Sweden for panic disorder and depression in some cases. We have 9 mg as the highest dose for long term treatment, 3 of the xanax depot 3 mg a day.
But the withdrawal of that. Man I don't even wanna think back to that time in my life.
I would not recommend it.
Posted by Lamdage22 on November 15, 2016, at 7:52:51
In reply to Re: Study: Increase GABA in Depressed Mice = AD effect, posted by Jonhed on November 12, 2016, at 5:39:08
Thanks for the warning.
This is the end of the thread.
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