![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 2 of 2. This is the beginning of the thread.
Posted by jaiho on October 11, 2015, at 3:37:28
NRIs such as Nortriptyline & Reboxetine block the tyramine reaction with MAOIs such as Nardil & Parnate.
Isn't it logical to add the NRI to an MAOI, to increase its efficiency and safety?I am currently on Nortriptyline 75mg, and looking to add Parnate.
Posted by SLS on October 12, 2015, at 21:41:46
In reply to Why doesnt every patient on an MAOI take an NRI?, posted by jaiho on October 11, 2015, at 3:37:28
> NRIs such as Nortriptyline & Reboxetine block the tyramine reaction with MAOIs such as Nardil & Parnate.
> Isn't it logical to add the NRI to an MAOI, to increase its efficiency and safety?Is this a theory or are there scientific studies that demonstrate this? I may have come across some animal studies, but I don't remember.
> I am currently on Nortriptyline 75mg, and looking to add Parnate.
I think most doctors still believe that such combinations are contraindicated. If MAOI monotherapy were to produce a remission in me, I would not want to take any other drugs and experience side effects or worse. Taking a NRI with a MAOI doesn't necessarily confer a reduced risk of the cheese reaction occuring. I suffered a reaction to a few slices of pepperoni while taking a combination of Parnate and desipramine. Once was enough. I currently take Parnate and nortriptyline.
- Scott
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.