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Dr. Bob is Robert Hsiung, MD,
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Posted by Dispossessed on March 31, 2015, at 20:52:01
An article on currentpsychiatry by Schwartz et al (2007) summarises how various antidepressants affect weight. I'm particularly interested by the findings that fluoxetine causes weight loss - though there is debate as to whether this occurs long-term rather than only in the acute phase.
Looking at the pharmacology of fluoxetine - why should it cause people to lose weight? It has negligible affinity for the norepinephrine and dopamine transporters. Aside from serotonin reuptake, it seems to be a fairly weak antagonist of 5ht2a and 5ht2c - but shouldn't this result in weight gain and an increased appetite (I'm thinking of mirtazapine here).
Posted by rjlockhart37 on March 31, 2015, at 23:43:21
In reply to Why should fluoxetine cause weight loss?, posted by Dispossessed on March 31, 2015, at 20:52:01
i've read from articles on the net that prozac can cause weigh gain, but not to extreme extent like zyprexa......
topamax and wellbutrin, and geodon from couple sources i read, can cause weight loss....
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