![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by Escapee on February 27, 2015, at 3:03:26
Hi . I've recently switched from amitriptyline 100mg at night to trimipramine 200mg at night. Much better response! Having a few vivid dreams n nightmares but I expected that with trimipramine as I've had it before. But no worse than from amitriptyline anyway. Now I'm on no SSRIs at all and feel a nudge better. What does that tell you! ?
I'm still gonna try lithium in about 2 months time.
Anyway. Does anyone know of any articles/abstracts (with references) that shows MAOIs can be switched quickly or even tapered together? In particular isocarboxazid (Marplan) to tranylcypramine (Parnate)? (Sorry I hate brand names)
My doc said we would need 7 to 10 days off isocarboxazid before the switch. Recently I read on here about switching from phenelzine to isocarboxazid whilst tapering together! I stopped phenelzine dead and then onto isocarboxazid after 3 days. Only because the pharmacy was out of stock or it would have been strait away. My decision NOT my docs.
So, can anyone help show what as safe despite what the (outdated?) text books say?
Posted by ed_uk2010 on February 27, 2015, at 4:04:06
In reply to MAOI to MAOI, posted by Escapee on February 27, 2015, at 3:03:26
First of all... have you been on tranylcypromine before and if so, how did you respond? Or would it be entirely new to you?
Posted by Lamdage22 on February 27, 2015, at 6:16:29
In reply to Re: MAOI to MAOI » Escapee, posted by ed_uk2010 on February 27, 2015, at 4:04:06
When i was at the hospital they switched back and forth between Parnate and Nardil with no concerns.
Posted by Escapee on March 1, 2015, at 11:05:43
In reply to Re: MAOI to MAOI » Escapee, posted by ed_uk2010 on February 27, 2015, at 4:04:06
> First of all... have you been on tranylcypromine before and if so, how did you respond? Or would it be entirely new to you?
>I've been taking MAOIs for 12yrs now. But this would be my 1st time on tranylcypromine.
Posted by ed_uk2010 on March 1, 2015, at 15:07:51
In reply to Re: MAOI to MAOI » ed_uk2010, posted by Escapee on March 1, 2015, at 11:05:43
>I've been taking MAOIs for 12yrs now. But this would be my 1st time on tranylcypromine.
There very little information to guide. A stroke has been reported when rapidly switching from phenelzine to tranylcypromine. Since you don't know how you respond to tranyl alone, there is additional reason to be cautious.
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.