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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by notredame1909 on January 16, 2015, at 4:12:50
Hi,
I'm diagnosed with anxiety disorder.
I'm currently taking Tianeptine 3 tabs 3 times a day. It helps me a lot (standard dosage 1-1-1 doesn't work), but didn't take all the anxiety off.
Another drug which helped me a lot was Amisulpride - 50 mg once daily.
Tianeptine (in higher dosages) and Amisulpride (in lower dosage)increase dopamine. And I think increasing dopamine helps my anxiety.
So I would like to add selegiline - 5-10 mg in the morning.
1. Can I take it with tianeptine? I know MAOI shouldn't be mixed with SSRI's and TCA'a, but tianeptine is SSRE (selective serotonin reuptake enhancer) and selegiline up to 10mg is MAO-B inhibitor (it only acts on dopamine).
So I would like to take tinaptine 3 tabs 3 times a day, and selegiline 1 tablet (5 or 10 mg) a day.2. If I cannot take selegiline with tianeptine, then I would like to take amisulpride 1 tab 50 mg a day, and selegiline 1 tab (5 or 10 mg) a day.
What do you think?
Thank you.
Posted by notredame1909 on January 17, 2015, at 7:36:25
In reply to Tianeptine or Amisulpride + Selegiline, posted by notredame1909 on January 16, 2015, at 4:12:50
Aby thoughts?
Posted by SLS on January 17, 2015, at 8:05:40
In reply to Tianeptine or Amisulpride + Selegiline, posted by notredame1909 on January 16, 2015, at 4:12:50
> Hi,
>
> I'm diagnosed with anxiety disorder.
>
> I'm currently taking Tianeptine 3 tabs 3 times a day. It helps me a lot (standard dosage 1-1-1 doesn't work), but didn't take all the anxiety off.
>
> Another drug which helped me a lot was Amisulpride - 50 mg once daily.
>
> Tianeptine (in higher dosages) and Amisulpride (in lower dosage)increase dopamine. And I think increasing dopamine helps my anxiety.
>
> So I would like to add selegiline - 5-10 mg in the morning.
>
> 1. Can I take it with tianeptine? I know MAOI shouldn't be mixed with SSRI's and TCA'a, but tianeptine is SSRE (selective serotonin reuptake enhancer) and selegiline up to 10mg is MAO-B inhibitor (it only acts on dopamine).
> So I would like to take tinaptine 3 tabs 3 times a day, and selegiline 1 tablet (5 or 10 mg) a day.
>
> 2. If I cannot take selegiline with tianeptine, then I would like to take amisulpride 1 tab 50 mg a day, and selegiline 1 tab (5 or 10 mg) a day.
>
> What do you think?
>
> Thank you.I would be hesitant to combine tianeptine with a MAOI unless you know a doctor who has experience with this. Despite tianeptine being described as being the "opposite" of a SSRI, I don't know what its secondary effects on serotonin pathways are. I did find this, though:
http://www.ncbi.nlm.nih.gov/pubmed/23048001
Amisulpride should be okay.
Regarding TCAs, you can mix MAOIs with desipramine or nortriptyline. I am currently taking Parnate with nortriptyline.
- Scott
Posted by notredame1909 on January 17, 2015, at 8:14:06
In reply to Re: Tianeptine or Amisulpride + Selegiline » notredame1909, posted by SLS on January 17, 2015, at 8:05:40
Thank you for your reply Scott.
Let's see what others might say.
In Poland docs dont't know much about ssre, and mixing it with maoi's.
This is the end of the thread.
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