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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by Scatterbrained on May 5, 2014, at 21:06:39
My doctor seems to think all atypicals are safe with maois but from what I read geodon more or less works as an SNRI combined with a neuroleptic. Definitely don't want to get into a toxic reaction . Does anybody have any insight into this?
Currently on
Parnate 40
Zyprexa 5
Lamictal 100
Posted by tom2228 on May 5, 2014, at 23:02:45
In reply to Parnate + Geodon safe?, posted by Scatterbrained on May 5, 2014, at 21:06:39
> My doctor seems to think all atypicals are safe with maois but from what I read geodon more or less works as an SNRI combined with a neuroleptic. Definitely don't want to get into a toxic reaction . Does anybody have any insight into this?
>
> Currently on
> Parnate 40
> Zyprexa 5
> Lamictal 100I would not recommend it
http://www.ncbi.nlm.nih.gov/pubmed/20631570
^(blank but another example)http://www.highbeam.com/doc/1P3-2365106271.html
^"Tranylcypromine/ ziprasidone interaction""A 41-year-old woman developed serotonin syndrome during treatment with ziprasidone and tranylcypromine for severe depression.
The woman had been receiving ziprasidone 40 mg [frequency, route and duration of therapy not stated] and started treatment with tranylcypromine at 10 mg/day [route not stated] after a 14 day washout of other medications. On day 23 the dosage of tranylcypromine was increased to 50 mg/day in divided doses. The next day she experienced tremors, shivering, diaphoresis, fever, vomiting, diarrhoea and confusion. She was admitted to an emergency department in an agitated state with a fever of 38.5°, a pulse of 130 beats/min, hyperreflexia, shivering and myoclonic jerks of all four extremities requiring restraints. "
Posted by Scatterbrained on May 5, 2014, at 23:25:11
In reply to Re: Parnate + Geodon safe?, posted by tom2228 on May 5, 2014, at 23:02:45
Thanks
Maybe it's time for me to find a new doctor. One who has the Internet in his office . Hard to come by when you are on Medicare.
Posted by phidippus on May 7, 2014, at 14:28:49
In reply to Parnate + Geodon safe?, posted by Scatterbrained on May 5, 2014, at 21:06:39
I would not mix Geodon with an MAOI exactly because it is an SNRI.
Eric
Posted by Scatterbrained on May 9, 2014, at 10:32:02
In reply to Re: Parnate + Geodon safe? » Scatterbrained, posted by phidippus on May 7, 2014, at 14:28:49
Yeah it's scary
Posted by Snell on May 15, 2014, at 7:00:00
In reply to Re: Parnate + Geodon safe? » tom2228, posted by Scatterbrained on May 5, 2014, at 23:25:11
I take 60 mg Parnate. So far I've combined it with Zyprexa, then Latuda, now Fanapt. No worries, no issues. Just potentiation of the antidepressant properties of the Parnate.
Posted by Catling on June 9, 2014, at 3:16:31
In reply to Parnate + Geodon safe?, posted by Scatterbrained on May 5, 2014, at 21:06:39
> My doctor seems to think all atypicals are safe with maois but from what I read geodon more or less works as an SNRI combined with a neuroleptic. Definitely don't want to get into a toxic reaction . Does anybody have any insight into this?
>
> Currently on
> Parnate 40
> Zyprexa 5
> Lamictal 100I know I'm a bit late with this comment, but in case anyone has this question in the future, I have been taking 40 mg parnate divided into 2 doses with 20mg geodon at bedtime for about a year with no problems. I have tried going up on the geodon but it makes me sleep too long (I'm very sensitive to meds).
I had very good results with the combo at first - decreased anxiety, decreased depression to the point where I could actually feel and sustain other emotions. It was great. Over time though the effects have worn off and it's back to the drawing board again.
I did have a particularly horrific interaction recently between parnate and latuda, but I notice that others seem to be taking that combo with no bad effects - so I think it's really just a matter of your own personal biochemistry and what's going to work for you.
This is the end of the thread.
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