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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by Noa on May 6, 2014, at 17:17:12
I had 4 days without Nefazodone (my dose is 500 mg) because I couldn't find a pharmacy that carried the dosage I needed and it was the weekend, etc. I have been feeling awful. Today I finally got it and took a dose 6 hours ago (an unusual time of day--I usually take it before bed but today it was mid-day) and still feel lousy. Nausea, mostly, but also 'cloudy-headed'.
The first couple of days I was ok, except for sleeping--needed extra ativan to sleep and even then sleep was not straight through. The past two nights were incrasingly worse. Last night, into this morning, I was nauseous in my sleep, nightmarish, feeling drugged and unable to wake up, etc. When I got out of bed I was really nauseous and unsteady. Have been taking it very easy all day. Managed to drive myself to the pharmacy to pick up the nefazodone and take it around noon. No driving since then--don't feel I can. Had a salt craving so I ate some potato chips and drank some water...was ok for a while but then more nausea. Thanks to my dogs, I did get out and take a couple of easy walks, which felt good, but afterward, the nausea returned (maybe also because I had a glass of water afterward?). Been feeling like sleeping but am avoiding it for 2 reasons---I think I'll be nauseaous if I lie down and I want to wait and take my regular dose and go to bed in a few hours.
How long until the withdrawal symptoms subside?
Posted by Phillipa on May 6, 2014, at 20:19:05
In reply to Nefazodone withdrawal symptoms, posted by Noa on May 6, 2014, at 17:17:12
That's serzone isn't it? Didn't know of anyone still using it. I would think that as soon as the levels build back up in your body you will feel a lot better. Sure hope you do. Phillipa
Posted by Hugh on May 7, 2014, at 10:51:28
In reply to Nefazodone withdrawal symptoms, posted by Noa on May 6, 2014, at 17:17:12
Of all the ADs I've been on, Serzone had the worst withdrawal symptoms. If I'd tapered it very slowly, I think I would have been fine, but I tapered too fast, and had intense withdrawal symptoms, but they were gone within a week.
Posted by Noa on May 7, 2014, at 12:30:08
In reply to Re: Nefazodone withdrawal symptoms, posted by Hugh on May 7, 2014, at 10:51:28
Thanks to both of you for your encouragement. I have now had 2 doses, a fairly decent night's sleep, and feel much better today--not perfect, but really improved.
Posted by jrbecker76 on May 7, 2014, at 16:39:38
In reply to Re: Nefazodone withdrawal symptoms, posted by Noa on May 7, 2014, at 12:30:08
> Thanks to both of you for your encouragement. I have now had 2 doses, a fairly decent night's sleep, and feel much better today--not perfect, but really improved.
My experience was that it took 2 weeks to peak the withdrawal but I'm fairly med sensitive.
I used to not believe that Nefazodone withdrawal was that intense, but more experience trying to reduce it proved me wrong.
I had a love-hate relationship with it. I typically saw good benefits from it in the hours after I dosed (at night) but would sometimes experience worsened mood, anxiety, and irritability during the afternoons and early evenings. I was pretty sure this was due to the m-CPP metabolite over-powering the effects of the parent drug in my system.
You could try cross-tapering to a >low dose< of Vistaril or Mirtazapine if getting off cold turkey proves too much, as both of these drugs have over-lapping receptor affinity. My personal recommendation would be for Vistaril.
Posted by Dr. Bob on May 8, 2014, at 22:29:37
In reply to Nefazodone withdrawal symptoms, posted by Noa on May 6, 2014, at 17:17:12
This is the end of the thread.
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