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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 20 of 20. This is the beginning of the thread.
Posted by Danielj on April 30, 2014, at 18:50:54
After care center had my son taking 3 Haldol 5 mg and 3 Wellbutrin and 1 20g Prozac. He developed severe EPS. Our regular pdoc recommended Latuda. The first 3 meds I mentioned were phased out over 2 weeks leaving just Latuda. I was encouraged in the beginningand yes after a month the EPS symptoms were mostly gone.
Now he is taking 1 80 mg Latuda a day at 9:00 PM. It's horrible he is so inconsistent from one day to the next it's unbelieveable his psychosis is breaking through big time after over 6 weeks on Latuda he is a ticking time bomb. Almost any sound or distraction will set him off. I am not certain if he is sleeping at all. He says he is but he is good at denial. I left a message for the pdoc but he didn't answer. Open to suggestions.
Posted by Danielj on April 30, 2014, at 19:08:00
In reply to I don't believe Latuda is working -Schizoaffective, posted by Danielj on April 30, 2014, at 18:50:54
I want to add that he is barely responsive when spoken to and does not get on his computer which has been his favorite thing to do for many years. Unbelievably he claims he is doing fine. His speech is delayed and delivered woodenly.
Posted by Christ_empowered on April 30, 2014, at 19:20:53
In reply to Re: don't believe Latuda is working, posted by Danielj on April 30, 2014, at 19:08:00
maybe add something? that might be easier than a switch over right now. Also, consider an anticonvulsant--trileptal, lamictal, something along those lines--to help the antipsychotic work better.
Sorry this is happening. Good luck to you.
Posted by LouisianaSportsman on April 30, 2014, at 21:01:06
In reply to I don't believe Latuda is working -Schizoaffective, posted by Danielj on April 30, 2014, at 18:50:54
I take Latuda 60mg. myself, but I'm not schizoaffective.
My favorites:
1. Invega
2. Saphris
3. Generic Perphenazine
4. Zyprexa
5. generic clozapine [depends on how many you've failed]
Posted by Phillipa on April 30, 2014, at 22:14:43
In reply to I don't believe Latuda is working -Schizoaffective, posted by Danielj on April 30, 2014, at 18:50:54
Daniel so sorry. You are such a great Dad. I personally can give no advise other than to keep calling and calling the pdoc. And if no response I would guess another trip to hospital. I know you don't want this but something isn't working right.. When you say go off. Do you mean explode? And their diagnosis is correct? And assuming you have had more than one doc since was hospitalized has seen your Son. Best of luck and please keep us posted. Phillipa
Posted by phidippus on May 1, 2014, at 14:22:34
In reply to I don't believe Latuda is working -Schizoaffective, posted by Danielj on April 30, 2014, at 18:50:54
The max dose for Latuda is 160 mg. Upping his dose may make a difference.
Eric
Posted by Danielj on May 1, 2014, at 15:49:56
In reply to Re: I don't believe Latuda is working -Schizoaffective » Danielj, posted by Phillipa on April 30, 2014, at 22:14:43
> Daniel so sorry. You are such a great Dad. I personally can give no advise other than to keep calling and calling the pdoc. And if no response I would guess another trip to hospital. I know you don't want this but something isn't working right.. When you say go off. Do you mean explode? And their diagnosis is correct? And assuming you have had more than one doc since was hospitalized has seen your Son. Best of luck and please keep us posted. Phillipa
He has been diagnosed by two doctors back in 2003 and again by one pdoc in 2013 and a different one in 2014. Three of the 4 doctors were at the same care center over the years. I took him food shopping today he seemed better, not as jumpy. I think the Latuda begins to wear off about 3PM but he is not due for a pill till 9PM. Even so he still seemed kind of unmedicated to me. Like sitting for hours in a chair without moving or saying anything. Not watching TV or going on computer when he is alone and both items (TV are right in front of him).
Posted by Phillipa on May 1, 2014, at 20:43:57
In reply to Re: I don't believe Latuda is working -Schizoaffective, posted by Danielj on May 1, 2014, at 15:49:56
Are you still trying to reach a doc? Undermedicated you say but if he just sitting there and not wanting to do things he likes could it be overmedicated? Phillipa
Posted by Danielj on May 1, 2014, at 22:46:12
In reply to Re: I don't believe Latuda is working -Schizoaffective » Danielj, posted by Phillipa on May 1, 2014, at 20:43:57
Ever since he first showed symptoms the first was akathisia = walking for hours and making faces and looking like he is talking to himself or somebody else. 3 months of 20 mg Zyprexa a day finally brought him out of it. That was 11 years ago.
Posted by Jeroen on May 2, 2014, at 2:30:05
In reply to Re: don't believe Latuda is working, posted by Christ_empowered on April 30, 2014, at 19:20:53
no lamictal, that's not recommended
more cognitive malfunction and memory problems
NOT RECOMMENDED!!
I recommend, Abilify 10 mg plus a low dose seroquel XR 150 mg is enough to combat psychosis
or if your doc wants to try minocycline added to the abilify, but then ditch the seroquel because of glutamate interaction
1 AP is enough with the minocycline (low dose to start)
abilify combatted my almost fatal psychosis in 2007, you need to take a benzo like ativan 2,5 mg with it for staying calm but hey it did help save my *ss for now
Posted by Christ_empowered on May 2, 2014, at 7:02:53
In reply to I don't believe Latuda is working -Schizoaffective, posted by Danielj on April 30, 2014, at 18:50:54
hey man...
I just read some PubMed stuff that remeron, @ 30mgs/day or more, helps treat akathisia from antipsychotics. I imagine it would help anxiety, sleep, tension, and mood problems, too. Its been studied as an add-on in schizo-disorders with good results. Its generic and cheap.
Maybe a combo therapy? I looked it up, and Abilify+loxapine is a surprisingly well-tolerated combination. I think Jeroen mentioned "AbiliQuel," the mix of Abilify and Seroquel.
Buspar has also been studied with antipsychotics, with some good results. I think its 2-3x daily dosing, though :-(
I'm on Abilify, and I recommend it to everybody. I take 30mgs/day, the biggest pill they make (and the highest FDA-approved dose). Maybe start on a high-ish dose of Abilify (my shrink started me on 20 back in the day) with some remeron, neurotin, hydroxyzine, or something to help with sedation?
Just throwing some ideas your way...
Posted by Phillipa on May 2, 2014, at 18:30:23
In reply to Re: I don't believe Latuda is working -Schizoaffective, posted by Danielj on May 1, 2014, at 22:46:12
Daniel at 11 years ago age then of Son?
Posted by Danielj on May 4, 2014, at 14:20:57
In reply to Re: I don't believe Latuda is working -Schizoaffective » Danielj, posted by Phillipa on May 2, 2014, at 18:30:23
My son was 15 years old 11 years ago when he was diagnosed schizoaffective.
Posted by Phillipa on May 4, 2014, at 20:44:40
In reply to Re: I don't believe Latuda is working -Schizoaffective, posted by Danielj on May 4, 2014, at 14:20:57
The age when so many are diagnoses or the symptoms of schizophrenia begin but you say schizoaffective? Phillipa
Posted by Danielj on May 10, 2014, at 19:07:44
In reply to Re: I don't believe Latuda is working -Schizoaffective » Danielj, posted by Phillipa on May 4, 2014, at 20:44:40
Phillip at one time in that early period he showed every sign of schizophrenia including walking backwards
and in odd patterns plus acute paranoia. He was also delusional but that was only when he was taking Abilify.
He hasn't been delusional since then. Abilify was the first med he took and he hated it.
Posted by Phillipa on May 11, 2014, at 18:15:05
In reply to Re: I don't believe Latuda is working -Schizoaffective, posted by Danielj on May 10, 2014, at 19:07:44
Daniel how is he doing now?
Posted by Danielj on May 14, 2014, at 12:49:13
In reply to Re: I don't believe Latuda is working -Schizoaffective » Danielj, posted by Phillipa on May 11, 2014, at 18:15:05
Phillip,
He is not doing well at all. Very stand offish and blunt. Denies everything. Everything is FINE like what do you want anyway, leave me alone attitude. Same way with Pdoc and he gave his therapist the boot. My guess is total paranoia, it's been years since he has been this bad. If he is Baker acted he will be off to the Florida State Hospital. The Pdoc didn't help at all, he upped his Latuda from 80 mg to 120 mg. In my opinion a dangerous move toward TD or EPS again.
Posted by Phillipa on May 14, 2014, at 20:41:59
In reply to Re: I don't believe Latuda is working -Schizoaffective, posted by Danielj on May 14, 2014, at 12:49:13
Daniel can you get another doctor for a second opinion. No doesn't sound like this med is working at all. Oh are you sure he's taking it and not cheeking it and then spitting it out? But he's living on his own isn't he? Would a depot injection be better? Phillipa
Posted by Zyprexa on May 20, 2014, at 20:03:21
In reply to I don't believe Latuda is working -Schizoaffective, posted by Danielj on April 30, 2014, at 18:50:54
Your son sounds like me. SchizoAffective, responds well to zyprexa, hates abilify, EPS from haldol. I had a bad number of years where I was not responding well to meds, my doc wanted me off zyprexa because I complained about weight gain. So I tried geodon and abilify and lamictal, stratera, remeron(which was worse than zyprexa, not a plesant effect, I would sleep all the time and apatite was worse than zyprexa). Not to mention the nightmares i had on it, just in one night off zyprexa.
After the abilify trials I was much worse off. Durring the 6 month trial the very low dose of zyprexa I was taking stoped working all together. I stoped the abilify and went back on high dose zyprexa. It had almost no effect like it did before the abilify. I would take 50mg of zyprexa with little effect. It took many years for the effects of abilify to were off and zyprexa start working again. But i also got TD real bad in my hands from abilify. So I couldn't soider at work any more, I still had the shakes uncontrolably some times and fear I could not work in electronics any more. I took 20mg z for a while, the 10mg z did not work anymore. Then I got on perphenazine, this is the only other AP that worked for me, but only in conjuction with the z. I now take 15mg generic teva z and 12mg x2 p. This has worked well for me over the last few years.
What Im recomending for your son is to go back on z, maybe a higher dose will work. Z worked for me in the beginning, 16 years ago and still works great to this day. I wish I had never gone on the medication merigoround. But it did help me deal with issues from my past.
Posted by Zyprexa on May 20, 2014, at 20:20:14
In reply to Re: I don't believe Latuda is working -Schizoaffective » Danielj, posted by Zyprexa on May 20, 2014, at 20:03:21
I should had mentioned that I have been self medicating since I was 16, off and on with alcohol and pot.
This is the end of the thread.
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