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Dr. Bob is Robert Hsiung, MD,
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Posted by brk23 on December 1, 2013, at 10:08:23
I have a newer reconized form of bipolar,there was a few hits on google but they are gone but when they were up the criteria matched me exact.Basicaly its called ULTRA RADEON i believe ,the differance is where most bi polar forms swing up and down via either days weeks or months,ULTRA RADEON has hard swings per hour so your going up and down through the day.
That is my problem,my antidepressants work,but i go from ok to down even on the hour.I desperatly need a good mood stablizer.problem is my depression is so sensative i cant handle any form of sedative except klonopin.
Klonopin actualy has been noted to have mood stablizing effects,and it does help me a LOT,however its not enough.
I tried all mainsteam meds from abilify to gedon and i hated them , ketamine in trials now has a cousin called MXE that was actualy believed to be better,THAT WORKED SO WELL it kept me stable,even allowed me to joke and laugh and last even held down my anger outbursts.
MXE has since been banned and i dont know what to take,im thinking something off label not mainstream any ideas would be helpful
Posted by ed_uk2010 on December 2, 2013, at 12:37:43
In reply to need help, posted by brk23 on December 1, 2013, at 10:08:23
Hi there,
Sorry to hear you're suffering again.
>I have a newer reconized form of bipolar,there was a few hits on google but they are gone but when they were up the criteria matched me exact.Basicaly its called ULTRA RADEON
It's called ultradian bipolar, not ultra radeon. There is still some good info on google, some from journals if you like that kind of thing.
Take care.
Posted by doxogenic boy on December 2, 2013, at 13:18:04
In reply to Re: need help, posted by ed_uk2010 on December 2, 2013, at 12:37:43
> It's called ultradian bipolar, not ultra radeon. There is still some good info on google, some from journals if you like that kind of thing.
I found this abstract about treatment of ultradian cycling:http://www.ncbi.nlm.nih.gov/pubmed/10357518
Quote:
J Child Adolesc Psychopharmacol. 1999;9(1):51-61.
Nimodipine treatment of an adolescent with ultradian cycling bipolar affective illness.
Davanzo PA, Krah N, Kleiner J, McCracken J.
SourceDepartment of Psychiatry and Behavioral Sciences, University of California, Los Angeles, USA.
AbstractThis is a single case report of an open trial of nimodipine, a dihydropyridine-type calcium antagonist, in the treatment of a 13-year-old boy with refractory, ultradian rapid cycling, bipolar disorder type I. Prior clinical trials with calcium channel blockers in adults with ultrarapid cycling affective disorder supported an empirical trial of nimodipine for treatment of ultradian rapid cycling in this adolescent. Severity of mania and depression were rated before and after nimodipine therapy. A marked decrease in rapid, repeated, and significant mood changes was clinically observed and measured by standardized scales after 9 days of nimodipine 180 mg daily. No adverse effects were noticed. Remission persisted with continued treatment at 36-month follow-up. Medication response was partially attributed to adjunctive therapy with levothyroxine. Implications of treatment benefit are discussed in the context of novel pharmacotherapies for refractory bipolar disorder. These findings are preliminary and do not provide sufficient basis to recommend nimodipine as the treatment of choice in adolescents with ultradian cycling bipolar disorder, but suggest that controlled studies may be indicated.
End quote.Excerpt:
If there are four mood episodes within a month, it is called ultra-rapid cycling, and when several mood switches occur within a day, on several days during one week, it is called ultra-ultra-rapid, or ultradian cycling. Typically, however, someone who experiences such short mood swings has longer episodes as well. Some individuals experience rapid cycling at the beginning of their illness, but for the majority, rapid cycling begins gradually. Most individuals with bipolar disorder, in fact, experience shorter and more frequent episodes over time if their illness is not adequately treated.
End quote.- doxogenic
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