Psycho-Babble Medication Thread 1045539

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Parnate: hungover from oversleeping?

Posted by vanvog on June 19, 2013, at 10:54:41


There is nothing about it in the literature and no reports on babble so maybe it's just me being weird.

I never had this before Parnate.

About every other week I have hypersomnia on Parnate, normally it's insomnia but it's alternating with insomnia on most days but once in a while I will be asleep anywhere from 12 to 20 hours.

Sometimes I forget to set my alarm clock, thinking I will be awake 3 hours later anyway, but if it's one of those hypersomnia instances, once I reach the threshold of 10 hours of sleep or more I will wake up with horrible hangover symptoms: headache, nausea, muscle pain, weakness, sensitivity to light and noise. It's really bad and it won't go away for a full day.

Has anyone ever heard of this?

 

Re: Parnate: hungover from oversleeping? » vanvog

Posted by tecknohed on June 24, 2013, at 8:52:30

In reply to Parnate: hungover from oversleeping?, posted by vanvog on June 19, 2013, at 10:54:41

Sorry I can't answer your particular question, but out of the 3 FULL MAOIs, Parnate is definitely the least stable. Many go from one extreme to another. And everyone seems to have their own unique strange effects/side effects with the med. Nardil is smooth and more predictable, so is Marplan.

teck

 

Re: Parnate: hungover from oversleeping?

Posted by cassandracomplex on June 25, 2013, at 18:26:06

In reply to Parnate: hungover from oversleeping?, posted by vanvog on June 19, 2013, at 10:54:41

I have idiopathic hypersomnia (diagnosis made while off medication). It is worsened SO much by Parnate. Parnate takes normal sleep and throws it out the window.

18 hours of sleep, inability to awaken in the morning, "sleep inertia" and "sleep drunkenness" ... Yep. I do experience a worsening of my condition with Parnate, but I've never known anyone else who developed it as a side effect without already being diagnosed with idiopathic hypersomnia or narcolepsy.

This is where psychostimulant augmentation comes in. I've been on combinations of very high dose Parnate and pretty high doses of Adderall/Dexedrine/Adderall XR/Dexedrine Spansules. The unfortunate thing is that wakefulness is just a "side effect" of stimulants so you become tolerant to it, which is why I am now using them on a PRN basis (I posted about this below).

Talk to a MAOI-friendly doc about stimulant augmentation - or perhaps first have a sleep study and see what's going on. There may be a better way to treat it if it really is drug-induced.


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