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Dr. Bob is Robert Hsiung, MD,
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Posted by Lamdage22 on May 11, 2013, at 11:25:41
In reply to Re: Damn it, its back. » Lamdage22, posted by Tomatheus on May 11, 2013, at 11:19:18
Thomateus,
yes, today i took 1mg and am fine.
Maybe it weakens. Idk
Posted by Tomatheus on May 11, 2013, at 11:52:14
In reply to Re: Damn it, its back., posted by Lamdage22 on May 11, 2013, at 11:25:41
Hi Lamdage22,
I'm glad that you seemed to notice less as far as restlessness/akathisia is concerned after you took your Akineton today. Have you had a chance to talk to your doctor about the Neurontin yet? Or have you decided to hold off on asking about that for now?
T.
Posted by Lamdage22 on May 11, 2013, at 13:20:36
In reply to Re: Damn it, its back. » Lamdage22, posted by Tomatheus on May 11, 2013, at 11:52:14
Well im in Hospital during the week. Psych Wards are pretty hierarchical here in Germany. The "top doc" said he wants to try approved meds first.
On monday my favorite Dr (who took on my case) is back, so i plan to ask her.
> Hi Lamdage22,
>
> I'm glad that you seemed to notice less as far as restlessness/akathisia is concerned after you took your Akineton today. Have you had a chance to talk to your doctor about the Neurontin yet? Or have you decided to hold off on asking about that for now?
>
> T.
Posted by SLS on May 11, 2013, at 15:28:07
In reply to Re: Damn it, its back., posted by Lamdage22 on May 11, 2013, at 11:23:43
> Hi Scott, mainly i want the Neurontin to counteract the inner restlessness feeling i currently get from Abilify. Possibly it is lightweight akathisia.
>
> Also, i have a bit of social anxiety.
>
> Lastly i have read about glutamate in Schizophrenia. When i took Lamictal without Antipsychotic, i had no psychosis.
>
>
I would think seriously about adding Lamictal and minocycline to your treatment regime.
- Scott
Posted by Lamdage22 on May 11, 2013, at 16:22:00
In reply to Re: Damn it, its back. » Lamdage22, posted by SLS on May 11, 2013, at 15:28:07
> I would think seriously about adding Lamictal and minocycline to your treatment regime.
>
>
> - ScottHi Scott,
yes, but how am i going to convince a "know it all" doctor to do that? I am thinking about lamictal, too. Hes like, yeah thats for bipolar, he says im unipolar. What the hell? Numerous Drs and Psychologists diagnosed me bipolar in the past.
Minocycline.. is that even safe long term?
Im thinking more about lamictal and neurontin.
Posted by Lamdage22 on May 11, 2013, at 16:22:46
In reply to Re: Damn it, its back., posted by Lamdage22 on May 11, 2013, at 16:22:00
I could buy it online without prescription, but doing things without doctor is always a pain in the b*ttocks.
Posted by Lamdage22 on May 12, 2013, at 4:43:31
In reply to Re: Damn it, its back., posted by Lamdage22 on May 11, 2013, at 16:22:46
Hey Scott,
what dosage for the minocycline?
Posted by SLS on May 12, 2013, at 7:08:21
In reply to Scott what dosage?, posted by Lamdage22 on May 12, 2013, at 4:43:31
> Hey Scott,
>
> what dosage for the minocycline?The dosage of minocycline most often studied for depressive and schizoid disorders is 200 mg/day.
Because you responded so well to Lamictal, I think you should think seriously about combining it with minocycline. The combination might work together to produce a greater degree of antiglutamatergic effect.
Minocycline:1. Is neuroprotective.
2. Reduces brain inflammation
3. Reduces the number of glutamate receptors.
4. Demonstrates antidepressant properties in mouse models of depression.
5. Is reported to act synergistically with noradrenergic antidepressants to treat depression - desipramine (but not fluoxetine).
6. Is reported to act synergistically with NMDA antagonists.
7. Reduces glutamate excitotoxicity by reducing the formation of quinolic acid, a NMDA agonist.
8. Reduces mitochondrial release of cytochrome C.
9. Modulates several signaling pathways.
10. Reduces microglial activation.
11. Has been reported anecdotally to successively treat depression.
12. Reduces the expression of lipopolysaccharide-induced pro-inflammation cytokines, an effect that acts as an antidepressant in animal models.
13. Increases neurite growth in response to nerve growth factor (NGF).
14. Inhibits high levels of PKC and GSK-3 alpha;
15. Decreases nitric oxide synthetase, thereby reducing free radicals which damage neurons and glia.
16. Reduces glutamate release.
- Scott
Posted by Lamdage22 on May 14, 2013, at 1:55:32
In reply to What to do against Abilify akathisia?, posted by Lamdage22 on April 28, 2013, at 6:10:43
The Geodon makes me tired, but in a different way than Zyprexa. More like a "normal" tired instead of "zombie tired".
Its day one so i hope it will work out for me.
Posted by SLS on May 14, 2013, at 6:46:17
In reply to They give me Geodon and Abilify now, posted by Lamdage22 on May 14, 2013, at 1:55:32
Hi Lamdage.
> The Geodon makes me tired, but in a different way than Zyprexa. More like a "normal" tired instead of "zombie tired".
>
> Its day one so i hope it will work out for me.I'm glad that your first dose of Geodon didn't produce somnolence or brain-fog. How much did you take?
Good luck!
- Scott
Posted by Tomatheus on May 14, 2013, at 11:38:42
In reply to They give me Geodon and Abilify now, posted by Lamdage22 on May 14, 2013, at 1:55:32
> The Geodon makes me tired, but in a different way than Zyprexa. More like a "normal" tired instead of "zombie tired".
>
> Its day one so i hope it will work out for me.Lamdage22,
I too would like to wish you luck with taking Geodon with Abilify.
T.
Posted by Lamdage22 on May 14, 2013, at 13:02:35
In reply to Re: They give me Geodon and Abilify now, posted by Tomatheus on May 14, 2013, at 11:38:42
I took two times 20mg. Morning and evening.
With currently 15mg Abilify.Akathisia like feeling was kinda strong today :(
Posted by Tomatheus on May 14, 2013, at 19:58:32
In reply to Re: They give me Geodon and Abilify now, posted by Lamdage22 on May 14, 2013, at 13:02:35
Hi Lamdage22,
I'm sorry to hear that the akathisia-like feeling seems worse now that you're taking the Geodon with your Abilify. I would probably try to give the Geodon/Abilify combo some time so you'll get an idea as to how it's going to affect you, unless things get really bad. I hope that somehow the akathisia will eventually subside some.
T.
Posted by Lamdage22 on May 15, 2013, at 1:56:39
In reply to Re: They give me Geodon and Abilify now » Lamdage22, posted by Tomatheus on May 14, 2013, at 19:58:32
I thought about taking the abilify at night perhaps..
That way i may have less of the akathisia. At night i usually feel ok.I know it has a long half life but anyway, isnt it worth a try?
Posted by Tomatheus on May 15, 2013, at 10:56:13
In reply to Re: They give me Geodon and Abilify now, posted by Lamdage22 on May 15, 2013, at 1:56:39
Yeah, taking Abilify at night might be worth trying. As you said, I don't know if it would make a difference given the medication's long half-life, but trying Abilify at night might be worth doing.
T.
Posted by Lamdage22 on May 15, 2013, at 13:43:10
In reply to Re: They give me Geodon and Abilify now » Lamdage22, posted by Tomatheus on May 15, 2013, at 10:56:13
Tomatheus you are on 5 mg Abilify as schizo-affective?
Posted by Tomatheus on May 15, 2013, at 14:23:31
In reply to Re: They give me Geodon and Abilify now, posted by Lamdage22 on May 15, 2013, at 13:43:10
> Tomatheus you are on 5 mg Abilify as schizo-affective?
>Yes. See the response that I just wrote to you on the other thread where you asked me about this for more details.
T.
Posted by Lamdage22 on May 19, 2013, at 4:54:20
In reply to Re: They give me Geodon and Abilify now » Lamdage22, posted by Tomatheus on May 15, 2013, at 14:23:31
Its becoming kind of unbearable.
Both Geodon and Abilify. I wish i could try Saphris.Im pretty unwell.
Posted by Lamdage22 on May 19, 2013, at 5:08:22
In reply to Re: They give me Geodon and Abilify now, posted by Lamdage22 on May 19, 2013, at 4:54:20
"Uuh Saphris is not approved for Schizophrenia in Germany, bla bla Diphenhydramine is approved as a sleep aid bla bla
Pissing me off.
Posted by Lamdage22 on May 19, 2013, at 6:57:10
In reply to Re: They give me Geodon and Abilify now, posted by Lamdage22 on May 19, 2013, at 5:08:22
> "Uuh Saphris is not approved for Schizophrenia in Germany, bla bla Diphenhydramine is approved as a sleep aid bla bla
>
> Pissing me off.On the plus side: Metformin seems to work against weight gain for me.
Posted by Tomatheus on May 19, 2013, at 11:39:40
In reply to Re: They give me Geodon and Abilify now, posted by Lamdage22 on May 19, 2013, at 4:54:20
Lamdage22,
I'm sorry to hear that you're not doing well. I hope that any changes that your doctor might make to your medication regimen will help you. Is it the akathisia from your medications that you're finding to be unbearable?
T.
Posted by Lamdage22 on May 19, 2013, at 13:22:43
In reply to Re: They give me Geodon and Abilify now » Lamdage22, posted by Tomatheus on May 19, 2013, at 11:39:40
Yes, its from Abilify. Im thinking Seroquel Aurorix and low dose Lithium right now. Higher doses give me palpitations.
With Metformin which absolutely works:)
Posted by Tomatheus on May 19, 2013, at 13:48:17
In reply to Re: They give me Geodon and Abilify now, posted by Lamdage22 on May 19, 2013, at 13:22:43
Lamdage22,
I'm sorry to hear that the akathisia has been as bad as it's been for you. I can only hope that the combo that you're considering will bring you the relief that you need without creating too many side effects, assuming that your doctor goes with what you're suggesting. I wish you the best of luck with everything.
T.
Posted by Lamdage22 on May 25, 2013, at 6:24:46
In reply to Re: They give me Geodon and Abilify now » Lamdage22, posted by Tomatheus on May 19, 2013, at 13:48:17
Thanks!
They discontinued abilify and have me on Seroquel now.
Posted by Tomatheus on May 25, 2013, at 11:15:15
In reply to Re: They give me Geodon and Abilify now, posted by Lamdage22 on May 25, 2013, at 6:24:46
Good luck with the Seroquel, Lamdage. Have you discussed the possibility of adding Aurorix and low-dose lithium with your doctor? If you have, what were your doctor's thoughts on adding those medications?
T.
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