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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 12 of 12. This is the beginning of the thread.
Posted by Roslynn on March 7, 2013, at 15:26:18
Hi all,
I have had to discontinue Parnate due to heart palpitations accompanied by pain. I am heartbroken. I've tried so many meds. Please don't tell me I made the wrong decision--I was really scared by the pain (not the palpitations themselves). I expected all kinds of side effects, but not this.
Anyway, back to the drawing board.
Roslynn
Posted by Hugh on March 7, 2013, at 15:51:54
In reply to Had to discontinue Parnate, posted by Roslynn on March 7, 2013, at 15:26:18
After years of trying and failing, I finally found a drug that eliminated my depression and anxiety, and I had to stop taking it because of side effects. In my case it was the muscle relaxant baclofen. Thanks to it, I got to discover what it was like to live normally, but only for a week. At least I know I can get to that place. I just need to find a different way of getting back there, and staying there this time. I think I'll try to join the ketamine trial that's going on all over the US.
Posted by Roslynn on March 7, 2013, at 15:57:54
In reply to Re: Had to discontinue Parnate, posted by Hugh on March 7, 2013, at 15:51:54
I just wanted to clarify...I've been experiencing heart palpitations since starting the Parnate (a month ago), and I did expect them, they are listed in the side effects, but it is just in the last few days that they have been accompanied by the pain.
Roslynn
Posted by Phillipa on March 7, 2013, at 18:10:38
In reply to Re: Had to discontinue Parnate, posted by Roslynn on March 7, 2013, at 15:57:54
Should be a topic of a thread strange side effects from meds. Sorry you had to discontinue. Phillipa
Posted by SLS on March 8, 2013, at 7:14:17
In reply to Had to discontinue Parnate, posted by Roslynn on March 7, 2013, at 15:26:18
> Hi all,
>
> I have had to discontinue Parnate due to heart palpitations accompanied by pain. I am heartbroken. I've tried so many meds. Please don't tell me I made the wrong decision--I was really scared by the pain (not the palpitations themselves). I expected all kinds of side effects, but not this.
>
> Anyway, back to the drawing board.
>
> Roslynn
I am disappointed to hear this. Was Parnate helping at all?I'm sure you'll come up with an alternate plan.
I'm really sorry... I know what it is like to be demoralized by a failed drug trial. It might help you to avoid despair by knowing that alternative treatments exist. It is far from certain that you are doomed. I wish I could help in some way.
What drugs are you currently taking?
Can you provide a detailed description of your symptoms and case history? Age of onset? Family history?
Have you ever responded favorably to treatment?
- Scott
Posted by Roslynn on March 8, 2013, at 14:31:16
In reply to Re: Had to discontinue Parnate » Roslynn, posted by SLS on March 8, 2013, at 7:14:17
Hi Scott,
Thank you so much for your concern and encouragement. I really appreciate it.
Do you ever turn on Babblemail or would you just get bombarded with questions? I'm just concerned at posting some of my detailed information on the public board.
Thank you,
Roslynn
Posted by Roslynn on March 9, 2013, at 10:26:06
In reply to Re: Had to discontinue Parnate » Roslynn, posted by SLS on March 8, 2013, at 7:14:17
Hi Scott,
Thank you so much for your concern and encouragement. I really appreciate it.
Do you ever turn on Babblemail or would you just get bombarded with questions? I'm just concerned at posting some of my detailed information on the public board.
Thank you,
Roslynn
>
>
> I am disappointed to hear this. Was Parnate helping at all?
>
> I'm sure you'll come up with an alternate plan.
>
> I'm really sorry... I know what it is like to be demoralized by a failed drug trial. It might help you to avoid despair by knowing that alternative treatments exist. It is far from certain that you are doomed. I wish I could help in some way.
>
> What drugs are you currently taking?
>
> Can you provide a detailed description of your symptoms and case history? Age of onset? Family history?
>
> Have you ever responded favorably to treatment?
>
>
> - Scott
Posted by brynb on March 12, 2013, at 4:12:30
In reply to Re: Had to discontinue Parnate, posted by Hugh on March 7, 2013, at 15:51:54
> After years of trying and failing, I finally found a drug that eliminated my depression and anxiety, and I had to stop taking it because of side effects. In my case it was the muscle relaxant baclofen. Thanks to it, I got to discover what it was like to live normally, but only for a week. At least I know I can get to that place. I just need to find a different way of getting back there, and staying there this time. I think I'll try to join the ketamine trial that's going on all over the US.
Hugh,
I've heard that at high doses, Baclofen is effective for anxiety. It helps depression, too? If you don't mind saying, what were the side effects that made you ditch it?
On another note, there's another doc here in Manhattan that opened a Ketamine clinic for pain and depression. Unlike Dr. Fruitman, he uses the IV route. At $480 an infusion, it's not horribly expensive, but Fruitman is only $250 per IM treatment.
-b
Posted by SLS on March 12, 2013, at 7:57:11
In reply to Re: Had to discontinue Parnate » Hugh, posted by brynb on March 12, 2013, at 4:12:30
> On another note, there's another doc here in Manhattan that opened a Ketamine clinic for pain and depression. Unlike Dr. Fruitman, he uses the IV route. At $480 an infusion, it's not horribly expensive, but Fruitman is only $250 per IM treatment.
The IV procedure has compelling documentation to show that it is robustly effective. I don't know about the IM procedure. From what I understand, it is important to hit a "zone" of partial unconsciousness in order for ketamine to work. Too much or too little fails to produce a therapeutic effect. I don't know if IM administration can be controlled well enough to bring one sufficiently into the zone for long enough so as to produce the results seen with the IV protocol.
http://mediasite.video.ufl.edu/Mediasite/Play/4a46e8f9a6f84560aadacc408f77f6b51d
- Scott
Posted by brynb on March 12, 2013, at 8:02:44
In reply to Re: Had to discontinue Parnate » brynb, posted by SLS on March 12, 2013, at 7:57:11
Hi Scott,
Thanks for the info. I will say, while not in remission, I'm a lot better than I was 6 weeks ago, and K's (done IM) antidepressant effect worked after only 2 or 3 treatments (in about 10 days).
I'm actually trying the IV route next week as an experiment in comparing the 2. I'm really interested in seeing/feeling the difference, if any.
-B
Posted by SLS on March 12, 2013, at 8:26:47
In reply to Re: Had to discontinue Parnate » SLS, posted by brynb on March 12, 2013, at 8:02:44
> Hi Scott,
>
> Thanks for the info. I will say, while not in remission, I'm a lot better than I was 6 weeks ago, and K's (done IM) antidepressant effect worked after only 2 or 3 treatments (in about 10 days).
>
> I'm actually trying the IV route next week as an experiment in comparing the 2. I'm really interested in seeing/feeling the difference, if any.
>
> -B
I am quite anxious to read your report. I am hoping that the IV produces in you the robust antidepressant effect that most often emerges four hours after infusion. Perhaps your current medications will allow the therapeutic effect of ketamine to persist. I don't know if this has been studied.http://www.ncbi.nlm.nih.gov/pubmed/22840761
- Scott
Posted by brynb on March 12, 2013, at 8:55:49
In reply to Re: Had to discontinue Parnate » brynb, posted by SLS on March 12, 2013, at 8:26:47
> > Hi Scott,
> >
> > Thanks for the info. I will say, while not in remission, I'm a lot better than I was 6 weeks ago, and K's (done IM) antidepressant effect worked after only 2 or 3 treatments (in about 10 days).
> >
> > I'm actually trying the IV route next week as an experiment in comparing the 2. I'm really interested in seeing/feeling the difference, if any.
> >
> > -B
>
>
> I am quite anxious to read your report. I am hoping that the IV produces in you the robust antidepressant effect that most often emerges four hours after infusion. Perhaps your current medications will allow the therapeutic effect of ketamine to persist. I don't know if this has been studied.
>
> http://www.ncbi.nlm.nih.gov/pubmed/22840761
>
>
> - ScottThanks, Scott. That's what I'm hoping for--enough Ketamine treatment supported by my AD to bring me to remission. I'll post an update :).
B
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