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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by novelagent on June 14, 2012, at 2:01:47
makes sense. When I was on it, the anhedonia I would get when I didn't take my Adderall was elliminated. It seems to have restorative properties...
http://jama.jamanetwork.com/article.aspx?volume=296&issue=1&page=31
Posted by SLS on June 14, 2012, at 5:53:08
In reply to JAMA: Aricept dampens meth craving, posted by novelagent on June 14, 2012, at 2:01:47
> makes sense. When I was on it, the anhedonia I would get when I didn't take my Adderall was elliminated. It seems to have restorative properties...
>
> http://jama.jamanetwork.com/article.aspx?volume=296&issue=1&page=31Nice article.
I hope your system is reregulated by donepezil such that you regain the ability to experience reward and pleasure. I will be very interested to read your follow-up posts.
Interestingly, Wellbutrin acts as a nicotinic receptor antagonist. A follow-up study evaluating the potential for Wellbutrin or Chantix (a partial agonist) to reverse the anti-craving effect of donepezil against methamphetamine cravings would be warranted, I think.
- Scott
Posted by Phillipa on June 14, 2012, at 10:26:40
In reply to Re: JAMA: Aricept dampens meth craving, posted by SLS on June 14, 2012, at 5:53:08
If aricept is for Alzheimers. I wonder if there is a connection between the two? Phillipa
Posted by linkadge on June 14, 2012, at 16:47:24
In reply to Re: JAMA: Aricept dampens meth craving, posted by Phillipa on June 14, 2012, at 10:26:40
IIRC Aricept is a sigma agonist (in addition to its effects on acetylcholinsterase). Sigma agonists have some anti-addictive effects.
Linkadge
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