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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by sheilac on March 22, 2012, at 13:51:31
I don't know if it's anxiety, akathesia or what is going on.
I take 600mg of Trileptal a day and it's doing a great job. Sometimes makes me feel flat though. So the doc suggested a small dose of Lithium for depression.
I've tried 300mg and 150mg and they both give me a feeling of hyperness and anxiety like feelings. The small dose of lithium dose lift my depression, but I am wondering if there is some sort of interaction between Lithium and Trileptal?
Why do I feel this way?
I think the Lithium helps me, but am I getting too much of some chemical in my brain? Is it just akathesia or anxiety brought on by the lithium add on?
Posted by SLS on March 22, 2012, at 16:06:36
In reply to Lithium Trileptal interaction?, posted by sheilac on March 22, 2012, at 13:51:31
> I don't know if it's anxiety, akathesia or what is going on.
>
> I take 600mg of Trileptal a day and it's doing a great job. Sometimes makes me feel flat though. So the doc suggested a small dose of Lithium for depression.
>
> I've tried 300mg and 150mg and they both give me a feeling of hyperness and anxiety like feelings. The small dose of lithium dose lift my depression, but I am wondering if there is some sort of interaction between Lithium and Trileptal?
>
> Why do I feel this way?
>
> I think the Lithium helps me, but am I getting too much of some chemical in my brain? Is it just akathesia or anxiety brought on by the lithium add on?
I can't answer your questions. Perhaps you can give lithium 150 mg a few more days before abandoning it.Akathisia is rare, but not unheard of with lithium. However, akathisia is a rather intense syndrome that is usually unmistakable to the person experiencing it. If you are having a reaction, it is very mild at this point.
I am not aware of any reasons why Trileptal and lithium would interact adversely.
I hope others here respond to your inquiry. Sorry I couldn't be more helpful.
- Scott
Posted by Sheilac on March 22, 2012, at 17:21:53
In reply to Re: Lithium Trileptal interaction? » sheilac, posted by SLS on March 22, 2012, at 16:06:36
Thanks Scott. It feels like the lithium gives me energy and anxiety. I tried moving my dose to the afternoon (so I won't be up all night going to the bathroom) and I think I need to have just a small amount of coffee in the morning.
Posted by dearsimone on May 25, 2012, at 11:50:40
In reply to Lithium Trileptal interaction?, posted by sheilac on March 22, 2012, at 13:51:31
Hi there. I was on tripletal (paired with cymbalta) for four years. All was successful. In 2006 I stopped both, to have a baby, then resumed both in 2007. After about a year I added lithium to the mix. Within a year something went wrong-I began to get very angry, have outbursts in front of the kids, etc. I stopped the Trileptal and went to Seroquel, and things improved.
It did not occur to me at the time that the problem could have been lithium, but it has since. I am about to go off lithium due to another issue, and am hoping dearly I can tolerate the Tripletal again. I suspect it is a much safer than Seroquel to be on longer term.
I have found on the internet some reference to problems between Tegretol, which is very similar to Trileptal, and Lithium. Nothing was in a language I understood much... something about
neurotoxities. Sounded important. I would surely like to know how that is relevant to our situations.Good luck.
This is the end of the thread.
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