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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 9 of 9. This is the beginning of the thread.
Posted by mogger on December 20, 2011, at 12:20:57
I think this is very interesting. I think I might ask my psychiatrist if I can try it.
Posted by Phillipa on December 20, 2011, at 21:01:55
In reply to high dose study of glycine for OCD, posted by mogger on December 20, 2011, at 12:20:57
Do you have body dysmorphic disorder? Sounds like for really impaired folks and a small study? Phillipa
Posted by mogger on December 29, 2011, at 23:32:25
In reply to Re: high dose study of glycine for OCD » mogger, posted by Phillipa on December 20, 2011, at 21:01:55
You are right Phillipa it does sound intense. Here is a more abbreviated version which doesn't sound so hardcore. :)
Posted by Phillipa on December 30, 2011, at 18:21:12
In reply to Re: high dose study of glycine for OCD » Phillipa, posted by mogger on December 29, 2011, at 23:32:25
Mogger I will goggle glycine. So atypicals made it worse? Phillipa
Posted by novelagent on January 5, 2012, at 19:09:53
In reply to Re: high dose study of glycine for OCD » mogger, posted by Phillipa on December 30, 2011, at 18:21:12
> Mogger I will goggle glycine. So atypicals made it worse? Phillipa
your doc can prescribe it via a compounding pharmacist-- it's presently a research drug in trials for negative symptom predominant schizophrenia, used as an adjunct with antipsychotics
Posted by novelagent on January 5, 2012, at 19:11:58
In reply to Re: high dose study of glycine for OCD » mogger, posted by Phillipa on December 30, 2011, at 18:21:12
> Mogger I will goggle glycine. So atypicals made it worse? Phillipa
your doc can prescribe it via a compounding pharmacist-- it's presently a research drug in trials for negative symptom predominant schizophrenia, used as an adjunct with antipsychotics
Posted by mogger on January 6, 2012, at 0:49:24
In reply to Re: high dose study of glycine for OCD, posted by novelagent on January 5, 2012, at 19:09:53
I thought that nmda antagonists were supposed to help depression and ocd but i see that glycine is a co agonist whatever that means? Seems to be contradictory.
Posted by SLS on January 6, 2012, at 6:07:27
In reply to Re: high dose study of glycine for OCD » novelagent, posted by mogger on January 6, 2012, at 0:49:24
> I thought that nmda antagonists were supposed to help depression and ocd but i see that glycine is a co agonist whatever that means? Seems to be contradictory.
Glycine is an inhibitory neurotransmitter - sort of like GABA. However, glycine acts as an allosteric co-agonist with glutamate at the NMDA receptor complex to open the ion channel. Both glutamate and glycine must be attached to the NMDA receptor at the same time. This is confusing. Glycine reuptake inhibitors enhance the efficacy of antipsychotics.
I need to learn more about the glutamate-glycine functional relationship. It does seem contradictory.
- Scott
Posted by Phillipa on January 6, 2012, at 19:37:56
In reply to Re: high dose study of glycine for OCD, posted by SLS on January 6, 2012, at 6:07:27
Scott if you don't understand it not many do? Certainly not me? Jan/P
This is the end of the thread.
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