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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by Phillipa on October 29, 2011, at 23:32:48
Was wondering why this med is not available in USA according to wiki it sounded pretty good for depression with anxiety and pain issues? Phillipa
Posted by jono_in_adelaide on October 30, 2011, at 18:31:06
In reply to Dosyleptin How Come In Europe + Not USA?, posted by Phillipa on October 29, 2011, at 23:32:48
do you mean dosulepin/dothiapin phillips?
That is the most widely used tricyclic in England, Europe and Australia...... its similar to nortriptyline, in that it is about equal to amitriptyline in antidepressant effects, but with far fewer side effects. Brand name is Prothiaden.
In these days of Effecor and Zoloft it isnt commonly used in depression, but it still finds a role in resistant patients, and also in chronic pain, fibromyalgia etc.
It was the first antidepressant i tried, at 150mg per day it worked, but the weight gain wasnt good.
Posted by Phillipa on October 30, 2011, at 20:58:12
In reply to Re: Dosyleptin How Come In Europe + Not USA?, posted by jono_in_adelaide on October 30, 2011, at 18:31:06
Jono a person on facebook has bad shoulders, back pain and insomnia and the NHS doc prescribed per her spelling dosyleptin and I googled it and it comes up yes fibro myalgia. Google see what you find Phillipa
Posted by jono_in_adelaide on October 31, 2011, at 6:44:24
In reply to Re: Dosyleptin How Come In Europe + Not USA? » jono_in_adelaide, posted by Phillipa on October 30, 2011, at 20:58:12
I think she's mis spelled it - dosulepin (previously called dothiepin, they changed the name for some reason) is a tricyclic that causes less drowsiness and side effects that amitriptyline - in the US, nortriptyline would be somthing very similar.
Until the "new" antidepressants came along, it was the one most commonly used in the UK, Australia, New Zealand and quite a few other countries. Nowadays it is, as you say, mostly used for chronic pain.
Posted by Phillipa on October 31, 2011, at 19:00:38
In reply to Re: Dosyleptin How Come In Europe + Not USA?, posted by jono_in_adelaide on October 31, 2011, at 6:44:24
Jono thanks today she facebooked that this med was too strong for her. Phillipa
Posted by jono_in_adelaide on October 31, 2011, at 19:23:42
In reply to Re: Dosyleptin How Come In Europe + Not USA? » jono_in_adelaide, posted by Phillipa on October 31, 2011, at 19:00:38
Tell her to ask her doctor for a trial of nortriptyline, 25mg at night for 1 week, then 50mg at night...... similar drug, but fewer side effects.
Posted by Phillipa on October 31, 2011, at 21:03:02
In reply to Re: Dosyleptin How Come In Europe + Not USA?, posted by jono_in_adelaide on October 31, 2011, at 19:23:42
Really don't talk meds there she mentioned switching meds for pain and too strong so went back to old med that works. Phillipa
Posted by ed_uk2010 on November 8, 2011, at 11:19:58
In reply to Re: Dosyleptin How Come In Europe + Not USA?, posted by jono_in_adelaide on October 30, 2011, at 18:31:06
> do you mean dosulepin/dothiapin phillips?
>
> That is the most widely used tricyclic in England, Europe and Australia...... its similar to nortriptyline, in that it is about equal to amitriptyline in antidepressant effects, but with far fewer side effects. Brand name is Prothiaden.The name was changed from dothiepin to dosulepin when the 'th' sound was removed from drug names. Most languages (except English) do not have the 'th' sound, making dothiepin unpronounceable.
Dosulepin is still sometimes prescribed in the UK by GPs, but not usually to new patients. It is extremely toxic in overdose, and is not generally used by psychiatrists. Amitriptyline (rather than dosulepin) is used a lot here for chronic pain.
This is the end of the thread.
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