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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by mantus on April 6, 2011, at 21:00:18
Hello,
If you have been following my posts you know I have been battling Nardil. I am now on 60mg which has a very small therapeutic effect, but have also been on 75mg which seems to help me a great deal more. The problem is my body appears to be hypersensitive to this med, and I continue to have side effect problems with no sign of improvement. On 75mg, I feel better, but I have severe insomnia and orthostatic hypotensions. Now on 60mg my sleep has improved, but my HR is raised and BP is too low. I'm a tired of feeling my resting HR now and it is in the 80's-90's when it has been in the 50-60 range my entire life. I especially hate when I stand up and my HR skyrockets to between 120-130. It makes me feel awful. My general BP is low and of course drops even lower when I stand, but I don't care so much about feeling dizzy every now and then, I just hate my HR issues. I feel like it is doing damage to my heart. I also noticed I can't workout hard, because my body just refuses to push itself, which I think has to be do to my low BP. If it is not that I'm really confused because I've always enjoyed working out and pushing myself. My biggest concern is that I will have to discontinue Nardil, when I feel like it is my last real medicinal option for improvement. For people that have had orthostatic hypotension issues while on Nardil, did your resting HR also go up and did you have difficulty exerting yourself? If the dizziness passed, did your hr also go back to normal and bp increase to normal levels without dropping so significantly when standing? I know some people take salt to increase their BP, but the problem is I still think my HR will be higher, which really doesn't help matters much. PLEASE, PLEASE give as many suggestions as possible, because I am completely lost right now and don't know what to do. I do not want to have to discontinue the Nardil until I can maybe try a higher dose again. I really don't want to add any more medications, as I am taking Ativan 1.5mg tid also (which I want to get off of). I guess, I just really want to know that if you have taken or are taking nardil or know anything about it, do you think my bp and hr will begin to normalize, because I have been on 60mg for several weeks, maybe a month, and although my sleep improved, my HR and BP aren't showing any signs of improvement at all. I have been on Nardil now for a little over 3 months total.Thanks,
Mantus
Posted by mtdewcmu on April 6, 2011, at 23:26:51
In reply to Nardil: Increased HR and Low BP are killing me, posted by mantus on April 6, 2011, at 21:00:18
Have you already tried Parnate, Marplan, and EMSAM?
Posted by lifelover on April 6, 2011, at 23:48:25
In reply to Re: Nardil: Increased HR and Low BP are killing me, posted by mtdewcmu on April 6, 2011, at 23:26:51
Mantus,sorry to hear ur struggling but dont give up on nardil! Maybe try augmenting it with a benzo such as a klonopin?A lot of people say they go good together. I havent ever tried this combo but Im pretty sure benzos lower ur heart rate.. Not sure how they affect ur blood pressure though. Im gona be augmenting nardil soon with lithium which from personal experience potentiates the effects of nardil quite a bit. Ive also read other reports online of it potentiating the effects of nardil for other people as well as a study that concluded that Nardil combined with lithium relieved depression in 3 severly depressed patients who had not responded to MAOI's alone... You should look into it seeing as its possible that you wouldnt need to be as high as 75mg to achieve those same effects, when lithium is added... Food for thought good luck my friend..
Posted by lifelover on April 7, 2011, at 0:08:14
In reply to Re: Nardil: Increased HR and Low BP are killing me, posted by lifelover on April 6, 2011, at 23:48:25
My b mantus the study had actually 4 patients who all failes to respond to trycicles, and 3 of them failed to respond to maoi's... But when lithium and nardil wer combined all 4 of them were relieved of their depression.
Posted by desolationrower on April 7, 2011, at 3:35:22
In reply to Nardil: Increased HR and Low BP are killing me, posted by mantus on April 6, 2011, at 21:00:18
i posted a new thread by accident, here:
Posted by Phillipa on April 7, 2011, at 11:29:44
In reply to Nardil: Increased HR and Low BP are killing me, posted by mantus on April 6, 2011, at 21:00:18
I'm sorry you are having such a hard time. I feel you could be right about energy and low BP. The higher heartrate could be trying to help raise your BP. Have you discussed this by phone with your doc lately maybe you should? Phillipa
Posted by emmanuel98 on April 7, 2011, at 19:09:25
In reply to Nardil: Increased HR and Low BP are killing me, posted by mantus on April 6, 2011, at 21:00:18
With orthostatic hypotension, your BP goes down and your HR goes up to compensate. Once you are up and about and your BP stabilizes, you HR should stabilize also.
Posted by jono_in_adelaide on April 11, 2011, at 17:37:28
In reply to Nardil: Increased HR and Low BP are killing me, posted by mantus on April 6, 2011, at 21:00:18
Ask your doctor for a trial of florinef, 0.1mg daily. It is a steroid drug used totreat addisons disease, and its main action is to cause retention of salt and water, causing an increase in BP - very effective in dealing with low BP/orthostatic hypertension, especialy if combined with a couple of salt tablets and some extra fluids.
As for the insomnia, one of the benzodiazepines or Z drugs should deal with this, and if Nardil is the only thing that works for you, it would certainly be appropriate.... say zoldipem 10mg at bedtime
This is the end of the thread.
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