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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by Economist on June 25, 2010, at 18:16:05
Someone here recommended I add desipramine or some other TCA to my current Prozac regimen to help with the anhedonia. Anyone here been on this combination?
Posted by SLS on June 25, 2010, at 19:24:39
In reply to TCA + Prozac combo for anhedonia?, posted by Economist on June 25, 2010, at 18:16:05
> Someone here recommended I add desipramine or some other TCA to my current Prozac regimen to help with the anhedonia. Anyone here been on this combination?
I have never tried this combination, but I have had limited success mixing Effexor and nortriptyline. The combination of Zoloft and nortriptyline is favored by some.
Any time you mix a TCA with either Prozac or Paxil, you must reduce the dosage of the TCA by at least half. These two SSRIs inhibit P450 2D6, the enzyme responsible for metabolizing the TCA, resulting in higher TCA blood levels.
- Scott
Posted by Conundrum on June 27, 2010, at 16:15:39
In reply to Re: TCA + Prozac combo for anhedonia? » Economist, posted by SLS on June 25, 2010, at 19:24:39
Which TCA are you thinking of adding?
Posted by X-ray on June 28, 2010, at 3:23:44
In reply to TCA + Prozac combo for anhedonia?, posted by Economist on June 25, 2010, at 18:16:05
> Someone here recommended I add desipramine or some other TCA to my current Prozac regimen to help with the anhedonia. Anyone here been on this combination?
Just don't mix Elavil and Prozac!
I've been on those two drugs.That was the worst time in my life.
X-ray
This is the end of the thread.
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