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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by vic80 on May 18, 2010, at 10:54:23
Lex Taper: down to 5mg today - 2.5 mg next 2 days and then stop.
Milnacipran: 25mg - 4th day4th day on MIL and I am beginning to feel such a rollercoaster of moods that is freaking me out - start the day with feeling totally out of it, dull and trapped in my head, withdrawn, but energy levels are ok
After breakfast (thats when I take MIL and Lex) -
sudden elevation of mood and energy levels - over-active, talkative and confident - freaks me out either coz its some sign of that widely abused term hypomania or maybe I have just not been in good spirits for months.The mood lasts for almost 1 hour, then starts to fizzle down a bit - I start to feel a bit irritated and short fused
another 1 hour : Feel the energy to do things, but not the drive or motivation - almost dissociative!
Antagonistic mood - bordering on agitation
Feeling very irritable now, mind feels frozen - cannot read write think or do anything - just anger - pacing up and down - almost at the verge of a violent outburst - but as though in control.Calm down in a bit - spirits are pretty down - not calm - but dysphoric - uninterested - energy levels are down to zero.
Food tastes much better - appetite has improved - physical stimulation by external stimuli - like touch, the breeze etc.
Sudden interest in talking to people - cordial with underriding and quite apparent caustic bitterness.
Sudden apathy and disinterest. Mental suffocation.
Almost a hypnotic state of mind.
Evening and late evening - dysphoria and fatigue - emotional overdrive - feel like crying, hugging people.
Sudden ruminations of the past - unstoppable self observation
Enhanced motivation to do things - but fizzles out with the mood.
Sudden irritability again before dinner followed by stupor and brain-deadness.
Post-dinner - elevated spirits, very concerned for family, making animated interesting conversations. Depersonalization symptoms seem to lift a bit - able to interact emotionally with my environment, confident of my own thoughts and seem to not have a life of their own. FEELING A BIT DRUNK rather DOPED.
Followed by dip in energy levels and gradual dip in mood - by the time I am in bed to sleep - mood stablizes - Lorazepam 0.5 and I am off to sleep in 20 minutes.
Apart from this mind is constantly popping with songs from TV, mobile ringtones, words and phrases from conversations I have had in the day or been a part of, words stuck in my head - this is definitely Lex withdrawal.
This is a rather long drawn desciption of my experience on Milnacipran 4 days. Not to mention a pulse rate which doesn go down below 96.
The feeling of a rock in my head is reminiscent of Mirtazapine - and even the increase in pulse rate - maybe the NE increase.
WhatI am scared of is that on 20 mg lexapro - i had no energy, used to have feelings of unreality, memory flashes, deja-vu blurred vision and disconnection.
This went away after I tapered down to 10 mg.I have had subtle similar feelings today - especially the drunk feelings and the casual deja-vu.
Is the high serotonin causing this?
NE could be behind the hyperactivity and irritability.
Any comments?
Posted by Phillipa on May 18, 2010, at 12:50:02
In reply to Milnacipran- Irritability hyperactivity Mood Swing, posted by vic80 on May 18, 2010, at 10:54:23
Does your doc know about the mood swings? What does family say or think? Phillipa
Posted by vic80 on May 18, 2010, at 13:05:50
In reply to Re: Milnacipran- Irritability hyperactivity Mood Swing » vic80, posted by Phillipa on May 18, 2010, at 12:50:02
> Does your doc know about the mood swings? What does family say or think? Phillipa
Havent talked to the pdoc yet, but family feels nothing abnormal about my behaviour - I guess I am too self-observant - blame my obsessive nature which got accentuated during my current anxiety-depression phase.
I guess I need to hold faith in Milnacipran - after all it was on my suggestion that the pdoc prescribed it. I think the pdoc thought 'fine, he cannot take Effexor, and we need to put him on an SNRI anyways, lets give him MIL, he's suggested it himself, he cannot complain later on'.
But nevertheless the alleviation of emotional numbness if only temporarily and casually holds promise for something good to look forward to in the future weeks.I have always noticed your replies to most of my posts, let me take this chance to thank you!
Posted by bleauberry on May 18, 2010, at 15:26:40
In reply to Milnacipran- Irritability hyperactivity Mood Swing, posted by vic80 on May 18, 2010, at 10:54:23
Split the 25mg of milnacipran in 3 doses and spread them apart equally throughout the day.
Do the same with the lex.
Posted by Phillipa on May 18, 2010, at 19:44:13
In reply to Re: Milnacipran- Irritability hyperactivity Mood Swing, posted by vic80 on May 18, 2010, at 13:05:50
Thanks that's sweet of you. Feeling a bit better now? Phillipa
This is the end of the thread.
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