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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 3 of 3. This is the beginning of the thread.
Posted by sowhysosad on October 24, 2009, at 9:18:52
Does anyone know of any drugs or, particularly, supplements that antagonise Sigma-2 receptors?
So far all I can come up with are Rimcazole and Ifenprodil.
One theory for EPS from uptake inhibitors is that they're caused by Sigma-2 agonism, so I thought it might be interesting to see whether symptoms are reduced by adding an antagonist.
Posted by Phidippus on October 25, 2009, at 2:03:53
In reply to Sigma-2 antagonists?, posted by sowhysosad on October 24, 2009, at 9:18:52
You found about the only two out there. There are a couple of other antagonists, but they are research drugs. Sigma-1 receptors are more widely programmed for ;)
Posted by sowhysosad on October 25, 2009, at 10:24:02
In reply to Re: Sigma-2 antagonists?, posted by Phidippus on October 25, 2009, at 2:03:53
> You found about the only two out there. There are a couple of other antagonists, but they are research drugs. Sigma-1 receptors are more widely programmed for ;)
Thanks!
I guess I might just avoid uptake inhibitors in future.
This is the end of the thread.
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