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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by rovers95 on October 11, 2009, at 17:19:37
Hi, my recent success with scopolamine has further made me think that i have developed a cholinergic problem after smoking and having an horrible reaction to choline citrate?
Does anyone know which antidepressants have the strongest anti-cholinergic action (iv read tricyclics...but which ones?!), as i believe i would struggle to obtain an anti-parkinsons med either through my doc or online,
thanks in advance,
rover
Posted by linkadge on October 11, 2009, at 17:54:10
In reply to best anticholinergic antidepressants?, posted by rovers95 on October 11, 2009, at 17:19:37
scopolamine, cogenitin (used for EPS), and the 1st gen TCA's (amitrip, imipramine, doxapin...)
Linkadge
Posted by rovers95 on October 12, 2009, at 14:03:03
In reply to Re: best anticholinergic antidepressants?, posted by linkadge on October 11, 2009, at 17:54:10
thanks mate, have you had any experience with them or do you know anyone who has responded to anti-cholinergic meds? im interested in congentin (if its an effective AD, cant find much medical literature in its favour) an bideperine (but it seems impossible to get hold of and i doubt my doc would prescribe.
However, i got some sort of pro-cholinergic with the scop and on withdrawal from smoking and am hoping this will not be the case with the above meds.
thanks
rover
Posted by linkadge on October 12, 2009, at 14:31:39
In reply to Re: best anticholinergic antidepressants?, posted by rovers95 on October 12, 2009, at 14:03:03
cogentin has no real studied effect in depression. It has anticholinergic effects. I believe it is also a weak dopamine reuptake inhibitor. It has abuse potential and may have antidepressant properties.
Amitriptyline is a potent anticholingeric and antidepressant. It would probably be easier to obtain.
Linkadge
Posted by rovers95 on October 19, 2009, at 14:47:31
In reply to Re: best anticholinergic antidepressants?, posted by linkadge on October 12, 2009, at 14:31:39
> cogentin has no real studied effect in depression. It has anticholinergic effects. I believe it is also a weak dopamine reuptake inhibitor. It has abuse potential and may have antidepressant properties.
>
> Amitriptyline is a potent anticholingeric and antidepressant. It would probably be easier to obtain.
>
> LinkadgeThanks again linkadge, from a few posts of yours i've seen it looks like perhaps your interested in long term anti-cholinergic mechanisms like myself, do you (or anyone else on the board) know of any med or even a herb, works in this manner?
Most of the stuff i've had a look at seems to cause a supersensitivity in acetycholine receptors following down-regulation and i believe both cigarettes (nicotine?) and scopolamine has had this effect on me?! like one of your posts i read im actually thinking if i went back to smoking long term i may be much better!
cheers
rover
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