![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 7 of 7. This is the beginning of the thread.
Posted by Frustratedmama on August 6, 2009, at 8:09:47
What time of day do you take pristiq AM or PM? I am still very fatigued and am considering taking it at night....wondering what others think? Why does a med that inhibits NE reuptake make me tired?
Posted by floatingbridge on August 6, 2009, at 11:07:18
In reply to NE and/or Pristiq users please read :), posted by Frustratedmama on August 6, 2009, at 8:09:47
Hi FM,
That darn fatigue! I take my 100 pristiq at night (my first week and half) (about an hour or two before bed) and I haven't needed a sleep aid at all. I am solid gone. I can't explain the NE effect, but I failed on wellbutrin--I could sleep on a 450 dose. (You recall that fatigue is a major issue for me.) Good luck, FM--thinking of you,
fb
Posted by SLS on August 6, 2009, at 12:53:15
In reply to Re: NE and/or Pristiq users please read :) » Frustratedmama, posted by floatingbridge on August 6, 2009, at 11:07:18
I don't know what the exact ratio is, but Pristiq is only slightly more potent at NE than Effexor. Both drugs are primarily serotoninergic. What's more, a drug like desipramine, a selective NE reuptake inhibitor, is sedating for many people, although this side effect usually dissipates. I guess this underscores how complex the brain is, and how variable are the properties of the drugs we use to treat it.
- Scott
Posted by Phillipa on August 6, 2009, at 13:25:32
In reply to Re: NE and/or Pristiq users please read :), posted by SLS on August 6, 2009, at 12:53:15
I thought pristiq was more sedating than effexor? Phillipa
Posted by ColoradoSnowflake on August 6, 2009, at 21:13:47
In reply to Re: NE and/or Pristiq users please read :) » Frustratedmama, posted by floatingbridge on August 6, 2009, at 11:07:18
> Hi FM,
>
> That darn fatigue! I take my 100 pristiq at night (my first week and half) (about an hour or two before bed) and I haven't needed a sleep aid at all. I am solid gone. I can't explain the NE effect, but I failed on wellbutrin--I could sleep on a 450 dose. (You recall that fatigue is a major issue for me.) Good luck, FM--thinking of you,
>
> fb
'Hi fb:
Same for me, I nodded right off on 450 mg Wellbutrin! But sometimes I would wake up 3 or 4 times in the night and obsess about something
It must be that awful fatigue factor.gayle
Posted by Frustratedmama on August 8, 2009, at 9:32:37
In reply to Re: NE and/or Pristiq users please read :), posted by ColoradoSnowflake on August 6, 2009, at 21:13:47
Thanks everyone!
Well, I am down to 1/4 of a 2 mg tablet of lunesta now (so 1/2 mg) and still able to sleep....think I will switch my pristiq to the nighttime to see if it helps! Also going to up the vyvanse from 30 to 50 mg......
I will keep you all posted!
FM
Posted by SheilaC on August 9, 2009, at 10:19:00
In reply to Re: NE and/or Pristiq users please read :), posted by Frustratedmama on August 8, 2009, at 9:32:37
I take my Pristiq around dinner. If I take it at bedtime I am hung over in the morning. If I take it in the morning I am tired all day long.
The only problem I have had with taking it at bedtime or dinner is that I still wake up in the middle of the night - wide awake and have a little trouble getting back to sleep.
Pristiq also really constipates me! Have you experienced this awful side effect? It's killing me.
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.