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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by SLS on June 18, 2009, at 16:08:32
Now that I have resolved my two-month Lamictal (lamotrigine) generic substitution fiasco, I have decided to revisit taking memantine, which I had thought was making me feel worse. Because I ended up relapsing more severely over time on the generic, I cannot properly evaluate how I would have responded to memantine had I remained on the name brand Lamictal. I am now up to 100mg of Topamax.
It was my idea to hit glutamate from 3 different directions:
1. Lamictal (lamotrigine): glutamate release inhibitor
2. Namenda (memantine): NMDA glutamate receptor antagonist
3. Topamax (topiramate): AMPA/kainite glutamate receptor antagonist.
I am somewhat optimistic.
Currently:Parnate 80mg
nortriptyline 150mg
Lamictal 200mg
Abilify 20mg
Namenda 20mg
Topamax 100mg
- Scott
Posted by Frustratedmama on June 18, 2009, at 20:12:08
In reply to Revisiting memantine (Namenda) - glutamate, posted by SLS on June 18, 2009, at 16:08:32
Stay optimistic, keep us posted, and good luck!
Posted by Phillipa on June 18, 2009, at 21:41:15
In reply to Re: Revisiting memantine (Namenda) - glutamate, posted by Frustratedmama on June 18, 2009, at 20:12:08
Someone who used to post here suggested memantine for me also. Will follow closely and Scott good luck. Love Phillipa
Posted by yxibow on June 19, 2009, at 1:42:36
In reply to Revisiting memantine (Namenda) - glutamate, posted by SLS on June 18, 2009, at 16:08:32
Remember memantine also agonizes D2, so its not completely innocuous, just watch out for that -- it probably wont affect you like it did me, but I think it pushed that spectrum for me. Who knows. It also antagonizes 5HT3, among other things.
-- Jay
Posted by SLS on June 19, 2009, at 4:31:43
In reply to Re: Revisiting memantine (Namenda) - glutamate, posted by yxibow on June 19, 2009, at 1:42:36
> Remember memantine also agonizes D2, so its not completely innocuous, just watch out for that -- it probably wont affect you like it did me, but I think it pushed that spectrum for me. Who knows. It also antagonizes 5HT3, among other things.
Hi Jay.I did NOT know either of those things.
Thanks!
- Scott
This is the end of the thread.
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