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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 9 of 9. This is the beginning of the thread.
Posted by Michael Bell on May 13, 2009, at 21:59:45
I guess this is something that we all kind of figured, but I had not seen a study on it yet. After all, the most effective substances for social anxiety (klonopin, nardil, GHB and alcohol) share the trait in that they all have major effects on GABA. Anyway here is the study showing that people with soical phobia have significantly less GABA in the medial prefrontal cortex, which may explain why gabaergic drugs work:
http://scnp.dk/journal/index.php/SCNP/article/view/77
Posted by shasling on May 13, 2009, at 23:29:11
In reply to Study shows social phobes have less GABA, posted by Michael Bell on May 13, 2009, at 21:59:45
i am a heavy ghb usser and ill tell you it does a lot more then simply increase gaba.
L theanine allegdedly increases blood and brain levels of both gaba and dopamine yet most people find it useless.
Technicaly i imagine the most potent gaba med would be GABTRIL as it is a gaba ruptake inhibitor and that has a bad track record on anxiety and depression etc.
All these chemicals and trying to make sense of them can alone cause u to go insane
Posted by Phillipa on May 14, 2009, at 0:20:33
In reply to Re: Study shows social phobes have less GABA, posted by shasling on May 13, 2009, at 23:29:11
If klonopin helps what about xanax and valium and even nueurotin or lydrica? Love Phillipa
Posted by Jay_Bravest_Face on May 14, 2009, at 4:37:07
In reply to Study shows social phobes have less GABA, posted by Michael Bell on May 13, 2009, at 21:59:45
Yes, but, over time, just taking benzos without an antidepressant can easily lead to depression.
It's not exactly if we have enough of "this" or "that", but a very, very complex interaction in various parts of the brain involving most neurotransmitters.Jay
Posted by Jimmyboy on May 14, 2009, at 8:11:48
In reply to Re: Study shows social phobes have less GABA » Michael Bell, posted by Jay_Bravest_Face on May 14, 2009, at 4:37:07
Alcohol is obviously the time tested quick remedy for social phobia . Too bad its not a long term solution. Anyone know what it effects other than GABA?
Posted by sam K on May 14, 2009, at 12:22:05
In reply to Re: Study shows social phobes have less GABA, posted by Jimmyboy on May 14, 2009, at 8:11:48
serotonin and dopamine
Posted by Phillipa on May 14, 2009, at 20:23:48
In reply to Re: Study shows social phobes have less GABA, posted by Jimmyboy on May 14, 2009, at 8:11:48
Unfortunately the liver. Phillipa
Posted by floatingbridge on May 15, 2009, at 16:41:49
In reply to Re: Study shows social phobes have less GABA » Michael Bell, posted by Jay_Bravest_Face on May 14, 2009, at 4:37:07
> Yes, but, over time, just taking benzos without an antidepressant can easily lead to depression.
> It's not exactly if we have enough of "this" or "that", but a very, very complex interaction in various parts of the brain involving most neurotransmitters.
>
> JayYes, I know from (sad) experience. Stimulants help SP as well--guess that's dopamine?
Candace
Posted by desolationrower on May 16, 2009, at 21:11:49
In reply to Re: Study shows social phobes have less GABA, posted by floatingbridge on May 15, 2009, at 16:41:49
> > Yes, but, over time, just taking benzos without an antidepressant can easily lead to depression.
> > It's not exactly if we have enough of "this" or "that", but a very, very complex interaction in various parts of the brain involving most neurotransmitters.
> >
> > Jay
>
> Yes, I know from (sad) experience. Stimulants help SP as well--guess that's dopamine?
> Candace
>well, that or na! plausible reasons either could be helping.
-d/r
This is the end of the thread.
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