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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 14 of 14. This is the beginning of the thread.
Posted by myco on April 5, 2009, at 20:04:57
D/r,
How much memantine do you take? Did you experiment with dose? Whats a good starting dose for maoi augment? I have to prepare info for tommorrow.
Also, if you can offer a suggestion here please, I need ideas for a DA/NE augment for maoi's. If I need more concentration & energy whats a good augment for that? Gp talk tommorrow. thnx
Myco
-------
Posted by myco on April 5, 2009, at 20:49:52
In reply to D/R: what's dosage of MEMANTINE? thnx, posted by myco on April 5, 2009, at 20:04:57
something to increase D2 receptor binding maybe? this is implicated in social anxiety - low D2 receptor binding
> D/r,
>
> How much memantine do you take? Did you experiment with dose? Whats a good starting dose for maoi augment? I have to prepare info for tommorrow.
>
> Also, if you can offer a suggestion here please, I need ideas for a DA/NE augment for maoi's. If I need more concentration & energy whats a good augment for that? Gp talk tommorrow. thnx
>
> Myco
> -------
Posted by Phillipa on April 5, 2009, at 21:28:25
In reply to Re: D/R: what's dosage of MEMANTINE? thnx, posted by myco on April 5, 2009, at 20:49:52
Priorities and you know what I mean. Love Phillipa
Posted by myco on April 5, 2009, at 21:40:17
In reply to Re: D/R: what's dosage of MEMANTINE? thnx » myco, posted by Phillipa on April 5, 2009, at 21:28:25
hehe i know babe. *hugs* im obsessed about my own treatment. I'll cool it for now
> Priorities and you know what I mean. Love Phillipa
Posted by Phillipa on April 5, 2009, at 21:47:25
In reply to Re: D/R: what's dosage of MEMANTINE? thnx » Phillipa, posted by myco on April 5, 2009, at 21:40:17
Just sent you some stuff. Please read them. Sweet man that you are. Love Jan
Posted by desolationrower on April 6, 2009, at 2:50:53
In reply to D/R: what's dosage of MEMANTINE? thnx, posted by myco on April 5, 2009, at 20:04:57
i take 20mg, 30-40 might be better
nortryptaline or reboxetine would be my choice but i mean anything useful is hard to get, guanfacine might give you. or weirder stuff modafinil pramiprexole
-0d/r
Posted by uncouth on April 11, 2009, at 12:22:44
In reply to Re: D/R: what's dosage of MEMANTINE? thnx, posted by myco on April 5, 2009, at 20:49:52
myco what do you mean about low D2 binding being implicated in social phobia?
Does that mean atypical antipsychotics can EXACERBATE SP? Since most of them (besides abilify) antagonize D2, correct? I'm on 120mg of Geodon....am I shooting myself in the foot on the social phobia dimension?
WIll adding 40mg of Memantine (which I have on order) help with social phobia?
Love,
-A
Posted by myco on April 11, 2009, at 12:41:25
In reply to Re: D/R: what's dosage of MEMANTINE? thnx » myco, posted by uncouth on April 11, 2009, at 12:22:44
AP's are not a good choice for social phobia based on what ive read.
Im fact, for atypical depressive with sever anxiety disorders like SAD or GAD, D2 antagonism is not a good idea. For me, using Seroquel at night for sleep (all i can get right now from dr), actually depresses me and adds to anxiety the next day from the night before. This is not uncommon among anxiety sufferers. In the beginning it seems Seroquel helped anxiety, to some extent, and carried on into the next day....but I dunno. Its different now. Name brand vs generic did help...less depression but it's still there.
But ya D2 is heavily implicated in social anxiety currently in the literature.
Memantine ive yet to try. Theoretically it should help (it does a variety of things including D2 inhibitor or something? cant remember exact mechanics-have to look up again). Some people report added energy. I'm gonna push the GP shortly on this one since its a safe mix with nardil.
I have a shitload of papers here, I can dig up some for you (many of which are not available online for free) if you want to have a look at some of the theory. But obsessing about literature theory isnt always the best approach. My recommendation is to give the theory a bit of attention then try and play with dose.
Babble mail me your email if you need papers....otherwise search pubmed:
(link: http://www.ncbi.nlm.nih.gov/pubmed/)
Search various terms: social phobia D2, anxiety dopamine, etc...
You will find tons of stuff...some contradictory but alot indicating dopamine plays a role.
myco
-------> myco what do you mean about low D2 binding being implicated in social phobia?
>
> Does that mean atypical antipsychotics can EXACERBATE SP? Since most of them (besides abilify) antagonize D2, correct? I'm on 120mg of Geodon....am I shooting myself in the foot on the social phobia dimension?
>
> WIll adding 40mg of Memantine (which I have on order) help with social phobia?
>
> Love,
> -A
Posted by Sigismund on April 12, 2009, at 21:04:02
In reply to Re: D/R: what's dosage of MEMANTINE? thnx » uncouth, posted by myco on April 11, 2009, at 12:41:25
I was vaguely thinking this morning of combining memantine with agomelatine, but was apprehensive about the effect on sleep.
Posted by myco on April 12, 2009, at 21:07:24
In reply to Re: D/R: what's dosage of MEMANTINE? thnx, posted by Sigismund on April 12, 2009, at 21:04:02
Sigi...what is your med regime....i cant remember?
> I was vaguely thinking this morning of combining memantine with agomelatine, but was apprehensive about the effect on sleep.
Posted by Phillipa on April 12, 2009, at 21:57:53
In reply to Re: D/R: what's dosage of MEMANTINE? thnx » Sigismund, posted by myco on April 12, 2009, at 21:07:24
Myco sometimes whiskey I think but not sure. And of course I could be wrong and probably am. I usually am. Love Phillipa PJ Jan
Posted by Sigismund on April 13, 2009, at 19:46:11
In reply to Re: D/R: what's dosage of MEMANTINE? thnx » Sigismund, posted by myco on April 12, 2009, at 21:07:24
agomelatine 25mg/d
diazepam 7.5-10mg/d
Posted by Sigismund on April 13, 2009, at 19:54:42
In reply to Re: D/R: what's dosage of MEMANTINE? thnx » myco, posted by Phillipa on April 12, 2009, at 21:57:53
I'm trying to be careful with that particular med.
Posted by desolationrower on April 14, 2009, at 2:40:11
In reply to Re: D/R: what's dosage of MEMANTINE? thnx » Phillipa, posted by Sigismund on April 13, 2009, at 19:54:42
i think you're confusing it with amantadine, which has a direct dopaminergic effect
-d/r
This is the end of the thread.
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