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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by meltingpot on March 13, 2009, at 14:21:21
Hi,
Well i've now completed my second week on Anafranil and the anxiety attacks seem to have subsided, I have more physical energy but I feel sort of emotionally numb.
Is this likely to continue. I don't particularly like how I'm feeling.
Denise
Posted by Phillipa on March 13, 2009, at 20:16:26
In reply to Second week on Anafranil - emotionally numb, posted by meltingpot on March 13, 2009, at 14:21:21
Denise good that the anxiety is gone. Maybe lower dose didn't know you were on it? Love Phillipa
Posted by zzzz7 on March 18, 2009, at 5:32:52
In reply to Second week on Anafranil - emotionally numb, posted by meltingpot on March 13, 2009, at 14:21:21
Clomipramine is a strong SRI; you may well get SSRI-like emotional blunting on it.
You might try adding some slight dopamine agonism (e.g. amantadine) with it to help with the blunting. Clom. also has some D2 blockade properties, though they aren't super-strong.
Posted by SLS on March 18, 2009, at 5:55:42
In reply to Second week on Anafranil - emotionally numb, posted by meltingpot on March 13, 2009, at 14:21:21
Hi Denise.
> Well i've now completed my second week on Anafranil and the anxiety attacks seem to have subsided, I have more physical energy but I feel sort of emotionally numb.
The side effects of Anafranil are a cross between those of a tricyclic and a SSRI. It is anyone's guess whether or not that numbness will disappear. However, if the drug works well, you will probably not notice it as much because the mind-activating properties of an antidepressant response should more than make up for a vague feeling of numbness. Also, you might be experiencing a sort of brain-fog that is almost certain to dissipate upon a robust improvement in depression. Feeling "weird" is sometimes a sign that good stuff is happening.
What dosage are you taking?
- Scott
Posted by Meltingpot on March 19, 2009, at 16:23:27
In reply to Re: Second week on Anafranil - emotionally numb » meltingpot, posted by SLS on March 18, 2009, at 5:55:42
Hi Scott,
Have gone up to 80mg. However, typing this my anxiety has got worst again and the suicidal thoughts and constant need to keep walking and walking (anxiety) started again.
Was feeling dreadful and my mother forced me to take zyprexa the last few nights as I was feeling increasingly suicidal.
I have lots of energy on the Anafranill but its like an anxious kind of unfocused energy. Feel like a scared child thoughout the day and then weak and apathetic in the evening.
I wouldn't be typing this now if it weren't for the Zyprexa I'd be sitting in my room thinking up ways of killing myself.
Zyprexa helps a lot but I don't particularly like how I feel on Zyprexa either but at least I feel a bit more hopeful after I've taken it.
What antidepressant is the least likely to exacerbate anxiety? I've tried Nardil before and although it didn't seem to be too bad anxiety wise, it did diddley squat for my depression.
I also wanted to ask you about Deep Brain Stimulation because I seem to remember you saying that there had been complications during the trials, is this the case?
One more thing, your cocktail of drugs, I know you've told me in the past and I know they work together but what does each drug do for you on it's own? What does Nardil do for you on it's own and then what does the tricyclic do for you on it's own?
Denise
This is the end of the thread.
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