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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by sigolene on June 27, 2008, at 8:06:28
what is the best med for schizophrenia negative symptoms, primary form. (i've never had positive symptoms).
And can ritalin be used for that ?
Posted by Horned One on June 27, 2008, at 8:45:11
In reply to primary negative symptoms schizophrenia, posted by sigolene on June 27, 2008, at 8:06:28
Low dose amisulpride or sulpiride are probably the best meds for negative symptoms.
-Horny
Posted by bleauberry on June 27, 2008, at 15:39:41
In reply to primary negative symptoms schizophrenia, posted by sigolene on June 27, 2008, at 8:06:28
Sigolene took the words right out of my mouth.
Genrally speaking I think negative symptoms require complex treatment to reach remission, involving any combination of two or three of these: antipsychotic, antidepressant, benzo, stimulant, dopamine agonist, and maybe even lamictal. But in clinical trials amisulpride did pretty good, as clinical trials go anyway.
Posted by mav27 on June 28, 2008, at 1:05:45
In reply to Re: primary negative symptoms schizophrenia, posted by bleauberry on June 27, 2008, at 15:39:41
Do you (or anyone) know if abilify has been shown to be effective in relieving negative symptoms?
Amisulpride worked for me for a while but then seemed to stop, i actually found 25mg worked better than 50mg for me.
Posted by bleauberry on June 28, 2008, at 20:22:24
In reply to Re: primary negative symptoms schizophrenia » bleauberry, posted by mav27 on June 28, 2008, at 1:05:45
> Do you (or anyone) know if abilify has been shown to be effective in relieving negative symptoms?
>
> Amisulpride worked for me for a while but then seemed to stop, i actually found 25mg worked better than 50mg for me.
I don't know actually. I assume anything that tweaks the dopamine circuits one way or another has a better chance than something else at targeting negative symptoms. Abilify with its mixed dopamine agonist/antagonist properties as well as serotonergic properties sounds to me, on paper anyway, like an appropriate choice. Maybe mixed with amisulpride?Prozac+adrafinil was pretty good on negative symptoms for me for a long time. Other people have had similar success with Modafinil added to ssris, or by itself.
This is the end of the thread.
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