![[dr. bob]](/dr-bob-sm.gif)
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by alexa35 on April 5, 2008, at 13:41:16
Can't they come out wih something better than what they have as my psychiatrist told me most of his patients with major depression do not respond to the drugs that have been out the past 10 years.
They sure haven't worked for me. Maybe I dot have a dopamine, seratonin or noeprehine (can't spell) problem. Aren't there many other chemical reasons one could suffer from depression?
Posted by star008 on April 5, 2008, at 15:38:13
In reply to Are there new AD drugs in our near future?, posted by alexa35 on April 5, 2008, at 13:41:16
there are always new ones.. my doc told me about a new effexor.. i am not sure what the difference is.. i don't remember what he said!! depressed.
there are always more and new ones but most of them don't work for those of us who have been through all of them.. but we keep trying anyway.. what choice do we have?? Effexor worked for me for about two years.. a record for me.. Then it pooped out.. There are all kinds of combinations and things docs can try.. Nothing seems to work for me but that doesn't mean there won't be something that will help you.. Try to keep some hope.. It is so hard.
Posted by Phillipa on April 5, 2008, at 16:53:31
In reply to Re: Are there new AD drugs in our near future? » alexa35, posted by star008 on April 5, 2008, at 15:38:13
Also a new long acting luvox. But that is an SSRI. Patented this time as brandname I believe though not positive. Phillipa
Posted by bleauberry on April 6, 2008, at 19:09:06
In reply to Are there new AD drugs in our near future?, posted by alexa35 on April 5, 2008, at 13:41:16
You asked if there are other things that cause depression besides serotonin, NE, and DA. Yes. Thyroid not optimal, regardless of normal looking lab numbers. Hypo adrenal function (low cortisol). Hidden fungal, viral, or bacterial infection...lots of toxins that love to dock on the opioid receptors. Mercury or lead exposure. Amalgam fillings. Food intolerances...lots of toxins that love to dock on the opioid receptors. One person here was cured after being diagnosed with sleep apnea. So yeah, there is a lot more to the game than just the 3 neurotransmitters. In my mind, the big 3 are adrenals, thyroid, and metal toxicity. To me they are big because they cause just about everything else that also causes depression. When those 3 are working optimally, many potential causes of depression are prevented, eliminated, or reduced.
New drugs? Yeah, but probably the same ole theories. Hey Lexapro is the better half of Celexa, so maybe that new Effexor will prove to be the same. If all the common antidepressants of about 40 other countries were suddenly FDA approved, there would be several new drugs. Milnacipran, Stablon, Adrafinil, just to name a few. People get those mailorder from overseas.
Posted by JayBTV2 on April 6, 2008, at 21:03:00
In reply to Are there new AD drugs in our near future?, posted by alexa35 on April 5, 2008, at 13:41:16
http://www.neurotransmitter.net/newdrugs.html
That lists new drugs in trials/etc.
Of those I think Valdoxan (agomelatine, AGO 178) is the most interesting. It's not a pure Serotonin/Dopamine/etc drug - it has some Melatonin action as well. From what I've heard the FDA/EU has been keeping it from getting approval though....
Hopefully there'll be some new stuff soon :)
-Jay
Posted by Phillipa on April 6, 2008, at 21:28:16
In reply to Re: Are there new AD drugs in our near future?, posted by JayBTV2 on April 6, 2008, at 21:03:00
About how to release would be your guess? Phillipa
This is the end of the thread.
Psycho-Babble Medication | Extras | FAQ
Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.org
Script revised: February 4, 2008
URL: http://www.dr-bob.org/cgi-bin/pb/mget.pl
Copyright 2006-17 Robert Hsiung.
Owned and operated by Dr. Bob LLC and not the University of Chicago.