Psycho-Babble Medication Thread 802411

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Bad anticholinergic effects of TCAs...Aricept???

Posted by addinbc on December 24, 2007, at 3:45:55

Hi there;

Last year, I gave desipramine a brief trial (8 weeks at very low doses) for ADD/anxiety/depression (any or all of them). I stopped it because I am apparently very sensitive to anticholinergic effects, and experienced really bad cognitive side effects while taking it.

I would like to give it another (more extensive) trial, and was wondering if a low dose of Aricept (or something similar) might help to reduce these anticholinergic effects.

Thank you, thank you!!

 

Bethanecol might help » addinbc

Posted by Racer on December 25, 2007, at 0:10:57

In reply to Bad anticholinergic effects of TCAs...Aricept???, posted by addinbc on December 24, 2007, at 3:45:55

Bethanecol is sometimes used to mitigate the anticholinergic side effects of TCAs and MAOIs. I think it's officially labeled for urinary retention, but it's a cholinergic agent which should help counter the rest of the problems these medications can cause.

Hope that helps.

 

Re: Bad anticholinergic effects of TCAs...Aricept?

Posted by cumulative on December 25, 2007, at 14:56:21

In reply to Bad anticholinergic effects of TCAs...Aricept???, posted by addinbc on December 24, 2007, at 3:45:55

Aricept or other cholinergic agents would probably be helpful, yes, both for offsetting these problems and (as is demonstrated with aricept) improving cognition.


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