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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 11 of 11. This is the beginning of the thread.
Posted by Jeroen on December 24, 2007, at 11:20:12
if you cut seroquel in half will it loose effect?
i have read Seroquel XR if you cut it in 2 parts the XR dissapears,
is it possible that the pill didnt work this time because a 200 mg tablet was split in 2 parts, i mean the IR not the XR.
i used 25 mg tablets in the past upto 100 mg and i got cured
Posted by yxibow on December 24, 2007, at 23:00:35
In reply to if you cut seroquel in half will it loose effect?, posted by Jeroen on December 24, 2007, at 11:20:12
> if you cut seroquel in half will it loose effect?
>
> i have read Seroquel XR if you cut it in 2 parts the XR dissapears,
>
> is it possible that the pill didnt work this time because a 200 mg tablet was split in 2 parts, i mean the IR not the XR.
>
> i used 25 mg tablets in the past upto 100 mg and i got cured
No, cutting 50s shouldn't matter, 25s are a bit of a crumb so its hard to say how much you're getting. Certainly splitting a 200 should give you somewhere around 100 on each side. Every medication is different of course, they generally try to put the main amount in the middle, but sometimes it isn't. If you aren't sure, ask your pharmacist.
If you leave cut pills around for a while they may lose their efficacy, that also depends on coating and volatility of the agent.
Posted by UgottaHaveHope on December 25, 2007, at 3:20:00
In reply to if you cut seroquel in half will it loose effect?, posted by Jeroen on December 24, 2007, at 11:20:12
nm
Posted by Phillipa on December 25, 2007, at 12:28:26
In reply to Re: if you cut seroquel in half will it loose eff » Jeroen, posted by yxibow on December 24, 2007, at 23:00:35
Split l2.5mg from 25mg once and it knocked me out. Good luck Jeroen. Phillipa
Posted by Jeroen on December 25, 2007, at 12:52:51
In reply to Re: if you cut seroquel in half will it loose eff, posted by Phillipa on December 25, 2007, at 12:28:26
seroquel XR may not be split, ... sais company
will loose it's XR effect if you do so...
soooooooo, i guess its true
Posted by yxibow on December 25, 2007, at 15:27:42
In reply to seroquel XR may not be split, ... sais company, posted by Jeroen on December 25, 2007, at 12:52:51
> seroquel XR may not be split, ... sais company
>
> will loose it's XR effect if you do so...
>
> soooooooo, i guess its trueWell you were just talking about IR.
XR is formulated to have a very short half life spread throughout a tablet or whatever blob they've put it in, you cut it, its like cutting 12 hour cough suppressants, you get a big rush at once and boom, nothing.
Posted by Jeroen on December 25, 2007, at 15:33:42
In reply to Re: seroquel XR may not be split, ... sais company » Jeroen, posted by yxibow on December 25, 2007, at 15:27:42
yes the IR can be split, but maybe this is the cause, i used to take 25 mg tablets in 2004 upto 100 mg and i felt good for the first time in years....
there are just so many factors here..
Posted by Phillipa on December 25, 2007, at 19:36:03
In reply to Re: seroquel XR may not be split, ... sais company, posted by Jeroen on December 25, 2007, at 15:33:42
Jeroen yes long acting xanax didn't work for me but the short acting does have heard the same from other people so same on your med can you go back to the other. Maybe that's whats needed. Phillipa
Posted by ace on December 25, 2007, at 22:26:48
In reply to if you cut seroquel in half will it loose effect?, posted by Jeroen on December 24, 2007, at 11:20:12
> if you cut seroquel in half will it loose effect?
Dependent on time. After the drug has been split in two, the 2nd part begins to oxidize (degrade).
Now, if you took that 2nd part 5 mins after the first part, you won't see much difference at all! However you take it 12+ hours later you will. As the time inceases the oxidation increases....a direct relationship.
Someone may have stated this in another thread, I'm not sure.
Generally better NOT to cut in half.
> i have read Seroquel XR if you cut it in 2 parts the XR dissapears,
>
> is it possible that the pill didnt work this time because a 200 mg tablet was split in 2 parts, i mean the IR not the XR.Not quite sure I understand what you mean here, but it's possible, very much so, the drug lost effect, wfater taking split portions.
> i used 25 mg tablets in the past upto 100 mg and i got curedGood to here. Seroquel have very practicle dose sizes...I wouldn't think you need to split it neceassarilly....
Ace!
Posted by UgottaHaveHope on December 26, 2007, at 3:04:17
In reply to Re: seroquel XR may not be split, ... sais company » Jeroen, posted by yxibow on December 25, 2007, at 15:27:42
Thats the only way to know for sure. Good luck, Michael
Posted by linkadge on January 1, 2008, at 20:29:13
In reply to Just split it and see how you feel ) Jereon, posted by UgottaHaveHope on December 26, 2007, at 3:04:17
I remember hearing about how seroquel had a lower risk of TD because of loose dissociation from the d2 receptors. But, if the drug is repeatedly dosed without a period for receptors to be unoccupied doesn't this defeat the purpose?
Linkadge
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