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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 4 of 4. This is the beginning of the thread.
Posted by Falstaff on December 20, 2007, at 6:48:03
I'm trying to figure out the best way to take Provigil for maximum effect. I have heard that at 200 or 300 mg it is 85% saturated so that taking more is almost useless but I'm not certain this is true.
Right now I take 400 mg in the morning and 200 mg around 2:00 pm. I'm fine in the morning but am still having trouble with sedation in the afternoon.
What are folks' experiences? Is it better to take it all at once? Does taking more really help? Anything else? Thanks!
- Kiki
Posted by Phillipa on December 20, 2007, at 12:15:23
In reply to How to Take Provigil T/O the Day for Max Effect?, posted by Falstaff on December 20, 2007, at 6:48:03
Different opinions I've read and some say don't take everyday or it will poop out. Phillipa
Posted by Racer on December 20, 2007, at 15:09:39
In reply to How to Take Provigil T/O the Day for Max Effect?, posted by Falstaff on December 20, 2007, at 6:48:03
I took it the way you do, a front-loaded split dose, and found that worked best for me. The active life of Provigil isn't all that long, so taking it all at once in the morning is more likely to lead to a bit of come down in the afternoon, rather than an all-day result.
If you're feeling a bit of a crash in the afternoons, you might be better off taking, say, 200mg at noon, then another 50mg about 4PM, just to ease the come-down.
Hope that helps.
Posted by bleauberry on December 21, 2007, at 18:17:10
In reply to How to Take Provigil T/O the Day for Max Effect?, posted by Falstaff on December 20, 2007, at 6:48:03
Not sure what you could do. I like to browse sites where patients review and rate their meds. Poopout and after-fatigue were common with provigil. I remember one guy did best at 1200mg a day! Opposite of logic, you could try a reverse loading dose. That is, start the day with a small dose, then make the second dose of the day the primary heavy hitter. Or maybe try 50mg every 2 hours, or 100mg every 3 hours, or something like that for a steady blood level. I guess you just gotta play around with it in every manipulation you can think of.
While all the focus is on provigil, I personally found that the drug it was invented from...adrafinil...was much better in terms of antidepressant, antifatigue, antianhedonia, and antipoopout. I think if I added up all the comments of people who have tried both adrafinil and provigil, 50% preferred adrafinil and 50% preferred modafinil. Anyway, they are similar and you might want to keep adrafinil on your watch list. Unlike provigil, adrafinil is dirt cheap.
This is the end of the thread.
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