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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 6 of 6. This is the beginning of the thread.
Posted by linkadge on March 27, 2007, at 7:15:35
Sleep deprivation alters monoamine concentrations. Many significant biochemical changes can happen after one night of sleep deprivation.
Somethinkg like 60% of severely depressed people will go into a state of euthemia with just one missed night of sleep (usually in a controlled environment though, not having to go to work the next day etc).
Anyhow, when I get less or no sleep, I feel better the next day. *Especially* on domains of feelings of self worth.
It is possable that my brain is trying to compensate for low mood by giving me insomnia?
Ie is insomnia a response to depression, and not just a symptom of it? Is the insomnia trying to induce monoamine alterations to compensate for mood problems?
Linkadge
Posted by Klavot on March 27, 2007, at 7:41:19
In reply to Insomnia to try and counteract monoamine disruptio, posted by linkadge on March 27, 2007, at 7:15:35
> It is possable that my brain is trying to compensate for low mood by giving me insomnia?
Perhaps there is no direct link between your insomnia and depression. Perhaps you feel better after a night of poor sleep because your body goes into survival mode, like a subtle fight-or-flight response.
Klavot
Posted by Meri-Tuuli on March 27, 2007, at 7:56:54
In reply to Re: Insomnia to try and counteract monoamine disruptio » linkadge, posted by Klavot on March 27, 2007, at 7:41:19
Its interesting. But what about atypical depressions? If anything, I tend to sleep more when depressed. However, I think thats just me wanting to block out the world - some people do it with drugs, drink etc, I just sleep.
Anyway, perhaps depressive feelings are less the next day, simply because you're too tired to care? You're just blah?
Posted by Phillipa on March 27, 2007, at 10:58:30
In reply to Re: Insomnia to try and counteract monoamine disru, posted by Meri-Tuuli on March 27, 2007, at 7:56:54
I feel horrible without a good night's sleep and that's at least 9 hours always been that way and one of my problems now is not getting that sleep. Love Phillipa
Posted by Cairo on March 31, 2007, at 21:51:35
In reply to Insomnia to try and counteract monoamine disruptio, posted by linkadge on March 27, 2007, at 7:15:35
I've felt that "I'm too tired to be tense" relaxation feeling after a couple of hours' worth lack of sleep. However, too much lack of sleep can make you more tense and ill. I went without 40 hours of sleep flying back from Japan last year (4 flights!) and I was physically ill for two weeks which made me hurt all over, tense and irritable. I felt like I had a bad case of the flu.
I wonder if it matter how much "building material" for the monoamine transmitters you inherently have that determines whether sleep deprivation and how much will boost mood. My guess is that it differs for everyone and where the genetic defect lies.
Cairo
> Sleep deprivation alters monoamine concentrations. Many significant biochemical changes can happen after one night of sleep deprivation.
>
> Somethinkg like 60% of severely depressed people will go into a state of euthemia with just one missed night of sleep (usually in a controlled environment though, not having to go to work the next day etc).
>
> Anyhow, when I get less or no sleep, I feel better the next day. *Especially* on domains of feelings of self worth.
>
> It is possable that my brain is trying to compensate for low mood by giving me insomnia?
>
> Ie is insomnia a response to depression, and not just a symptom of it? Is the insomnia trying to induce monoamine alterations to compensate for mood problems?
>
> Linkadge
>
>
>
>
>
>
>
Posted by psychobot5000 on April 1, 2007, at 13:32:55
In reply to Insomnia to try and counteract monoamine disruptio, posted by linkadge on March 27, 2007, at 7:15:35
> Sleep deprivation alters monoamine concentrations. Many significant biochemical changes can happen after one night of sleep deprivation.
>
> Somethinkg like 60% of severely depressed people will go into a state of euthemia with just one missed night of sleep (usually in a controlled environment though, not having to go to work the next day etc).
>
> Anyhow, when I get less or no sleep, I feel better the next day. *Especially* on domains of feelings of self worth.
>
> It is possable that my brain is trying to compensate for low mood by giving me insomnia?
>
> Ie is insomnia a response to depression, and not just a symptom of it? Is the insomnia trying to induce monoamine alterations to compensate for mood problems?
>
> Linkadge
>
It sort of seems to me that, if your body's systems are 'smart' enough to be trying to alter your monoamine concentrations, they might do so directly. ....As opposed to using sleep deprivation to force a decrease in catacholamine metabolism, etc. ... It seems like an awfully circuitous and innefficient way for your body to correct its own problems.Supposing your body is in a sort of dysregulated homeostasis (neurotransmitter-wise), then wouldn't your body's miscalculations as tot he proper balance of chemicals be a source of the problem, rather than being an agency aimed at solving it? It also seems to me that, given that depressive insomniacs already may have disrupted monoamine systems, that that alone ought to be enough to prevent proper sleep--too much anxiety or stimulation, say.
But who knows...
This is the end of the thread.
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