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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 15 of 15. This is the beginning of the thread.
Posted by Tom Twilight on November 24, 2006, at 12:32:33
Hey all
I'm sorry for the elaborate title!
I've read lately that there is quite a significant relationship between Inflamation & an Overactive Immune system and Depression.
Does anyone know anything about this?
Further more could Immuno supressant Drugs and Supplements & Anti Inflamitories possible help with Depression?
Posted by Jimmyboy on November 24, 2006, at 12:45:47
In reply to Inflamation-Imune System Depression, posted by Tom Twilight on November 24, 2006, at 12:32:33
I have been suffering from severe depression for along time and just got back from a very cutting edge clinic that do all kinds of new tests I have never heard of.. but time and time again the physiological things that kept popping up was signs of inflammation in my body.
Immune system was screwed up, amount of oxygen getting in my tissues and brain was way low, all of this due to inflammation, supposedly. Uh, they didn;t really give me an answer of why there was inflammation , but it begs the question : What came first the inflammation causing the depression or vice versa ??
Of course I like to think the inflammation caused the depression ... that makes it more physical, thus maybe other people out there could be a littl emore understanding and acceptable.. but then again who gives a sh&* as long as all of us could get to feeling better.
Anyway, on the alternative board we were talking about glutathione and depression , its pretty interesting stuff.. it has lots of effects on inflammation, immune system etc.. check it out over there..
JB
Posted by Phillipa on November 24, 2006, at 12:56:50
In reply to Re: Inflamation-Imune System Depression, posted by Jimmyboy on November 24, 2006, at 12:45:47
I have autoimmune thyroid and possible liver. Rheumatologist said at one time I may be a miss mash of a lot of autoimmune disorders. And the chronic lymes. Tom do you think this is contributing to the depression? Love Phillipa
Posted by Declan on November 24, 2006, at 12:58:11
In reply to Re: Inflamation-Imune System Depression, posted by Jimmyboy on November 24, 2006, at 12:45:47
Depression is a symptom cluster.
Inflammatory markers can be measured.
A reduction in inflammation may lead to a reduction in depression.
Which inflammatory markers are we talking about?
Posted by Tom Twilight on November 24, 2006, at 13:26:08
In reply to Re: Inflamation-Imune System Depression, posted by Declan on November 24, 2006, at 12:58:11
> Depression is a symptom cluster.
> Inflammatory markers can be measured.
> A reduction in inflammation may lead to a reduction in depression.
> Which inflammatory markers are we talking about?Well I understood the first sentence :)
Seriously what is is an "Inflamtory Marker"?
This is a really interesting discussion!God I wish I didn't live in the UK, I doubt doctors here have any idea that inflamation & depression can be linked
P.S. Sorry to have been out of touch Declan
I've just not being doing so well lately
Posted by Quintal on November 24, 2006, at 15:09:58
In reply to Re: Inflamation-Imune System Depression, posted by Tom Twilight on November 24, 2006, at 13:26:08
This inflammation thing is interesting. I have been getting attacks of cellulitis (gross swelling and inflammation of the ankles) for about 4 years now which the docs tell me is very rare in anyone under 40, and I was only 20 when it started. When I was in hospital they wanted to keep me in longer because the inflammatory markers were so high despite all external inflammation disappearing. I decided to leave anyway but now I'm thinking I may have done the wrong thing. The doc at hospital also asked if there was a family history of Chron's disease, which there is (my mother had an aggressive form and was crippled by it) - along with other autoimmune inflammatory conditions.
I was reading about Quercetin over on alternative and have ordered some. Would this be helpful for this inflammation/prostaglandin thing?
Suggestions anybody? Do I go back to the doc and request a blood test, and on what grounds other than I've been feeling unwell lately, which could just be a flare up of my hypochondria afterall?
Q
Posted by blueberry on November 24, 2006, at 17:20:34
In reply to Inflamation-Imune System Depression, posted by Tom Twilight on November 24, 2006, at 12:32:33
Over the years I have noticed that when I take ibuprofen or advil to reduce swelling or pain, a notice improved mood for a few hours.
Posted by Declan on November 24, 2006, at 17:31:49
In reply to Re: Inflamation-Imune System Depression, posted by Tom Twilight on November 24, 2006, at 13:26:08
Hi Tom
Well, C reactive protein might be one. And the one with the cool name, tumour necrosis alpha, might be another. There might be lots. My knowledgeable nutritional doctor, the holistic one, said from looking at my 4hr glucose tolerance test that inflammation was lessened, but how he knew that I don't understand. I wasn't going to ask more then. Someone has to pay for good medicine and I'd paid enough at that point.
Nardil is pretty tough on your body then, Tom? The trouble with conventional medicine is that it assumes wellness except in the symptom area, but often the symptoms are aggravated by the fact that we are unwell (not to speak of lonely).
Declan
Posted by stargazer on November 24, 2006, at 19:30:50
In reply to Re: Inflamation-Imune System Depression, posted by blueberry on November 24, 2006, at 17:20:34
My comments/questions on this post...
Prednisone, a very common drug used to treat inflammation, i.e. asthma, lupus, crohn's, etc, can cause a sense of euphoria in those treated with it. A common symptom upon discontinuation from it can be depression. Because of this, it can be very difficult to reduce the dosage
You should only be on Prednisone for short periods of time since it greatly reduces the immune system's ability to fight infection, making you suseptible to acquiring infection, due to leukopenia(low white cell count).
Jimmy Boy...I'm interested in finding out what treatment was recommended to you after specific deficiencies and abnormalities were identified by their sophisticated testing.
Also, the post regarding cellulitis of the ankles and/or legs came up in another post and had me thinking about side effects from medications, specifcally combining as more an more people are combining numerous variety of medications. That would be the first thing to think of when you have edema in your legs, hands or feet. It is never normal and can be a serious side effect of medication. It can also be an early sign of kidney and/or heart failure and should be evaluated by an MD ASAP.
Stargazer
Posted by Quintal on November 24, 2006, at 19:55:17
In reply to Re: Inflamation-Imune System Depression, posted by stargazer on November 24, 2006, at 19:30:50
Well I did read that clonazepam can cause bleeding into the tissues or something of that nature, I don't remember exactly, but I was afraid to mention it at the time in case they forced me to withdraw immediately. Was the person on the other thread taking clonazepam (Klonopin) stargazer?
I had an ECG at the hospital on admission and it was normal. Kidney and liver function was normal I think. It was just the inflammatory markers that were way too high, but by then they'd ruptured a vein in my arm with a cannula and filled the tissue with caustic cephalexin solution. I just wanted to escape before they could cause any more harm. So I don't know if those inflammatory markers ever came back within normal range or why they were so high in the first place.
Q
Posted by Phillipa on November 24, 2006, at 20:06:07
In reply to Re: Inflamation-Imune System Depression, posted by blueberry on November 24, 2006, at 17:20:34
Blueberry strange as I've noticed when I take ibuphropen at night I sleep better with the middle of the night valium. Figured I get hot around 4am and this lowers my temperature hence sleeping better not hot. Love Phillipa
Posted by Phillipa on November 24, 2006, at 20:34:51
In reply to Re: Inflamation-Imune System Depression, posted by stargazer on November 24, 2006, at 19:30:50
I know prednisone, cortisone it killed my Mother when it first came out in the 50's they didn't know you couldn't take it indefinitely. And it causes or can cause psychosis whle taking it too. Love Phillipa happens each Spring when my sister gets a pack of prednisone for poison ivy.
Posted by Jimmyboy on November 25, 2006, at 1:20:47
In reply to Re: Inflamation-Imune System Depression, posted by stargazer on November 24, 2006, at 19:30:50
Well, afetr all of that testing , they basically said.. " there is imflammation but be are not sure why" , so a sort of shotgun approach was given, they suggested raising glutathione, fish oil , vitamins, antiviral medication, thyroid T3( mine was borderline low) , testosterone cream, I am not sure what is helping, but I feel better...
No antidepressants, except a small amount of SAMe , and I used to take 10X what I'm taking now...
Hopefully will keep helping..
JB
Posted by Tom Twilight on November 26, 2006, at 16:08:41
In reply to Re: Inflamation-Imune System Depression » stargazer, posted by Jimmyboy on November 25, 2006, at 1:20:47
Assuming inflamation is part of the problem, what can be done about it?!
Are there any supplements or meds that could help?
Posted by Declan on November 26, 2006, at 17:48:09
In reply to Inflamation-OK What can be done!, posted by Tom Twilight on November 26, 2006, at 16:08:41
Will this work? will this help?
http://www.lef.org/protocols/prtcl-146a.shtml
This is the end of the thread.
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