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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 8 of 8. This is the beginning of the thread.
Posted by MARTY on April 17, 2006, at 2:46:44
Hi Big Brains ;)Hope you're all well.
I will soon start Parnate after a deceiving Nardil trial and I'm NAIVELY wishing I could do/try something to keep the more I can from the initial "High" or at worst workout the bad things about Parnate: fatigue, sleepiness, reduce chance of poop out etc...
I read some post about Memantine and I think SLS has even tried it.
Respected Veterans, ;) Could you resume me what have been tried and succeed/failed and what could be try ? I'm even ready to give my brain to science (if I get at least a veterans vote of 60%... LOL)
Plz give me an hand on this.. My soon new start on Parnate is very important for me and I would like to, like everyone else, put every chances on my side.. even if it's highly theoric.
Marty
Posted by MARTY on April 17, 2006, at 2:47:42
In reply to VETERANS: MEMANTINE + PARNATE ? Logic+Experiences?, posted by MARTY on April 17, 2006, at 2:46:44
Posted by MARTY on April 17, 2006, at 2:54:02
In reply to VETERANS: MEMANTINE + PARNATE ? Logic+Experiences?, posted by MARTY on April 17, 2006, at 2:46:44
For so many reasons I feel this is the most intelligent and incredible Post Title to ever appear on Dr.Bob ... :)Click here for a brand new hard to answer post!
http://www.dr-bob.org/babble/20060412/msgs/634050.html
;) Thanks guys. I wish one day I could too be put in such a title :PMarty
Posted by SLS on April 17, 2006, at 6:35:41
In reply to VETERANS: MEMANTINE + PARNATE ? Logic+Experiences?, posted by MARTY on April 17, 2006, at 2:46:44
Hi Marty.
There is evidence that memantine will help opioids work better as pain medications. However, there is less evidence regarding its addition to stimulants.
Adding memantine to Parnate might help. When I added memantine 20mg to imipramine and Lamictal, I responded to it briefly. I doubt memantine will produce any adverse reactions. In Germany, where memantine has been available for over 10 years, some doctors do use it to treat depression. However, it is probably of limited value because it is used so little. Unfortunately, there are not many investigations in American medical literature to evaluatate its efficacy in the treatment of depression. The one study performed by the NIH failed to demonstrate efficacy.
I guess the bottom line is that there are no disadvantages to adding memantine to Parnate other than its cost. There is very little scientific evidence that it is effective in the treatment of major depressive disorder. However, there are a few reports of its use in Germany.
- Scott
> I will soon start Parnate after a deceiving Nardil trial and I'm NAIVELY wishing I could do/try something to keep the more I can from the initial "High" or at worst workout the bad things about Parnate: fatigue, sleepiness, reduce chance of poop out etc...
>
> I read some post about Memantine and I think SLS has even tried it.
>
> Respected Veterans, ;) Could you resume me what have been tried and succeed/failed and what could be try ? I'm even ready to give my brain to science (if I get at least a veterans vote of 60%... LOL)
>
> Plz give me an hand on this.. My soon new start on Parnate is very important for me and I would like to, like everyone else, put every chances on my side.. even if it's highly theoric.
>
> Marty
Posted by SLS on April 17, 2006, at 7:02:17
In reply to Re: VETERANS: MEMANTINE + PARNATE ? Logic+Experien, posted by SLS on April 17, 2006, at 6:35:41
Unfortunately, there are not many investigations in American medical literature to evaluatate its efficacy in the treatment of depression. The one study performed by the NIH failed to demonstrate efficacy.
>
> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16390905&query_hl=1&itool=pubmed_docsumYou know, I think there is a major problem with the way psychiatric drugs are evaluated. It is expected that one drug be able to treat an illness monotherapeutically. This leaves out the possibility that some very effective augmentors become available. For instance, ritanserin by itself might not be effective as an antidepressant, but it would probably be great as an augmentor to standard antidepressants because it is a potent 5-HT2 antagonist. It is used now only in lab experiments. The same can be said of gepirone as a 5-HT1a partial agonist. As of now, if a drug is discovered to be an augmentor, it is only by accident with one that is already available to treat other illnesses. The mentality of the drug companies is to produce a single compound that performs multiple tasks. It might be more productive to produce a variety of molecules that are selective to perform one task so as to be used in combination with other selective agents. This is the sort of strategy used to develop treatments for other illnesses like AIDS.
- Scott
Posted by Crazy Horse on April 17, 2006, at 9:00:15
In reply to ACE + SLS + Ed + Ace + Dec + Med + Djmm + Link+CH, posted by MARTY on April 17, 2006, at 2:54:02
>
> For so many reasons I feel this is the most intelligent and incredible Post Title to ever appear on Dr.Bob ... :)
>
> Click here for a brand new hard to answer post!
>
> http://www.dr-bob.org/babble/20060412/msgs/634050.html
>
>
> ;) Thanks guys. I wish one day I could too be put in such a title :P
>
> MartyOh, i see how you are, you put me last on the list...almost as an afterthought!! (just kidding)
Marty, what are you taking now?
I highly recommend taking Parnate alone or maybe with a benzo. Don't starting adding a lot of chemicals, let parnate work on it's own. Keep things simple at least for a couple of months. Don't start anticipating incorrectly how you will feel on parnate. You might not even get the afternoon fatigue, so just wait and see.I can understand you wanting to be ready just in case, i did the same thing. But, please trust me on this, take the parnate without adding other meds, so you can see if the PARNATE works, and if and when it does i promise you will not need add on agents, at least not right away.
una co da seaka lo pata...relax my friend, give the powerful parnate a chance! :)
-Crazy Horse
Posted by MARTY on April 17, 2006, at 15:33:58
In reply to Re: VETERANS: MEMANTINE + PARNATE ? Logic+Experien, posted by SLS on April 17, 2006, at 6:35:41
So their not much evidence or logic proposin memantine as a possible agent to stretch to the maximum the initial "euphoria / well being" of MAOIs...Is there any other agents that could help to / do that ? .. or any kind of strategy ? I can't believe we all everytime has to touch the sky just to fall to a mixed weird level where you are stimulated/tired/sleepy etc.. Their should be a was to leverate the effect a bit more than that !?
If it does that.. if it does the same thing as Nardil I'm back to point 0. And then there is not much left to try... that's sadMarty
> Hi Marty.
>
> There is evidence that memantine will help opioids work better as pain medications. However, there is less evidence regarding its addition to stimulants.
>
> Adding memantine to Parnate might help. When I added memantine 20mg to imipramine and Lamictal, I responded to it briefly. I doubt memantine will produce any adverse reactions. In Germany, where memantine has been available for over 10 years, some doctors do use it to treat depression. However, it is probably of limited value because it is used so little. Unfortunately, there are not many investigations in American medical literature to evaluatate its efficacy in the treatment of depression. The one study performed by the NIH failed to demonstrate efficacy.
>
> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16390905&query_hl=1&itool=pubmed_docsum
>
> I guess the bottom line is that there are no disadvantages to adding memantine to Parnate other than its cost. There is very little scientific evidence that it is effective in the treatment of major depressive disorder. However, there are a few reports of its use in Germany.
>
>
> - Scott
>
>
> > I will soon start Parnate after a deceiving Nardil trial and I'm NAIVELY wishing I could do/try something to keep the more I can from the initial "High" or at worst workout the bad things about Parnate: fatigue, sleepiness, reduce chance of poop out etc...
> >
> > I read some post about Memantine and I think SLS has even tried it.
> >
> > Respected Veterans, ;) Could you resume me what have been tried and succeed/failed and what could be try ? I'm even ready to give my brain to science (if I get at least a veterans vote of 60%... LOL)
> >
> > Plz give me an hand on this.. My soon new start on Parnate is very important for me and I would like to, like everyone else, put every chances on my side.. even if it's highly theoric.
> >
> > Marty
>
>
Posted by MARTY on April 17, 2006, at 15:48:39
In reply to Re: ACE + SLS + Ed + Ace + Dec + Med + Djmm + Link+CH » MARTY, posted by Crazy Horse on April 17, 2006, at 9:00:15
Haha I did put you last because your name is soo long! and I was sur you would care enough to answer me anyway my friend :) ehehI understand your point. That's what I'll do. But I asking myself "If.. IF! I could take something to make the initial euphoria episode last near forever..." .. you know.. I was so good on the Nardil initial euphoric episode.. When it did get away I've found it very hard.. fatigue started, tiredness.. MUCH LESS MOTIVATION/ENERGY etc..
anyway.. chance I found something to achieve this is near zero.. if nobody hear had succes achieving this my chance a near 0.000001 ..
But if someone very knowledgeable would have something to propose, a new idea.. I could think about it.. For the Science! ;)
Marty ..> >
> > For so many reasons I feel this is the most intelligent and incredible Post Title to ever appear on Dr.Bob ... :)
> >
> > Click here for a brand new hard to answer post!
> >
> > http://www.dr-bob.org/babble/20060412/msgs/634050.html
> >
> >
> > ;) Thanks guys. I wish one day I could too be put in such a title :P
> >
> > Marty
>
> Oh, i see how you are, you put me last on the list...almost as an afterthought!! (just kidding)
>
> Marty, what are you taking now?
> I highly recommend taking Parnate alone or maybe with a benzo. Don't starting adding a lot of chemicals, let parnate work on it's own. Keep things simple at least for a couple of months. Don't start anticipating incorrectly how you will feel on parnate. You might not even get the afternoon fatigue, so just wait and see.
>
> I can understand you wanting to be ready just in case, i did the same thing. But, please trust me on this, take the parnate without adding other meds, so you can see if the PARNATE works, and if and when it does i promise you will not need add on agents, at least not right away.
>
> una co da seaka lo pata...relax my friend, give the powerful parnate a chance! :)
>
> -Crazy Horse
This is the end of the thread.
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Dr. Bob is Robert Hsiung, MD,
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